AB180585

重组Anti-C16orf45抗体[EPR14087]

Anti-C16orf45 antibody [EPR14087]

RabMAb
Recombinant
了解详情

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(1 Publication)

Rabbit Recombinant Monoclonal C16orf45 antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication.

查看别名

C16orf45, BMERB1, bMERB domain-containing protein 1

2 Images

Supplier Data

Western blot - Anti-C16orf45 antibody [EPR14087] (AB180585)

All lanes:

Western blot - Anti-C16orf45 antibody [EPR14087] (ab180585) at 1/5000 dilution

Lane 1:

Human fetal brain tissue lysate at 10 µg

Lane 2:

Human adrenal gland tissue lysate at 10 µg

Secondary

All lanes:

Anti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1000 dilution

Predicted band size: 24 kDa

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Supplier Data

Western blot - Anti-C16orf45 antibody [EPR14087] (AB180585)

All lanes:

Western blot - Anti-C16orf45 antibody [EPR14087] (ab180585) at 1/5000 dilution

All lanes:

A673 cell lysate at 10 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Predicted band size: 24 kDa

false

不同偶联物与剂型 (1)

Carrier free

Anti-C16orf45 antibody [EPR14087] - BSA and Azide free

关键信息

宿主种属

Rabbit

克隆

Monoclonal

克隆号

EPR14087

亚型

IgG

不含载体蛋白

反应种属

Human

应用

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "<p></p>" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }

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产品详情

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

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性能和储存信息

形式

Liquid

纯化工艺

Affinity purification Protein A

存储溶液

Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA

运输条件

Blue Ice

分装信息

Upon delivery aliquot

储存信息

Avoid freeze / thaw cycle

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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

C16orf45 is a protein encoded by the C16orf45 gene also known in the scientific community as Chromosome 16 open reading frame 45. The exact mass of this protein remains under investigation but it is generally expressed throughout human tissues with higher expression noted in certain cancerous tissues. Researchers continue to explore its distribution to understand its varied roles in different cellular contexts.

Biological function summary

The C16orf45 protein appears to participate in cellular processes linked to proliferation and differentiation. While exact interactions at the molecular level are not fully mapped some studies suggest its involvement in forming part of a multi-protein complex that may influence these processes. As such it could have broader implications for understanding basic mechanisms controlling cell behavior.

Pathways

Current research has identified some connections between C16orf45 and key cellular signaling pathways such as the MAPK/ERK pathway. This pathway is important in transmitting signals from the cell surface to the DNA within the nucleus affecting cellular activities like division and growth. C16orf45 may interact closely with proteins like ERK helping to modulate the outcomes of this pathway and possibly impacting gene expression modifications.

Altered expression patterns of C16orf45 have been linked to specific cancer types notably breast cancer. The protein appears to interact with oncogenes like HER2 possibly influencing cancer progression or resistance to therapies. Researchers aim to further dissect these relationships as C16orf45 could serve as a potential biomarker or a novel therapeutic target in oncology.

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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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靶点信息

See full target information BMERB1

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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Developmental cell 57:387-397.e4 PubMed35134345

2022

The Lipid Droplet Knowledge Portal: A resource for systematic analyses of lipid droplet biology.

Applications

Unspecified application

Species

Unspecified reactive species

Niklas Mejhert,Katlyn R Gabriel,Scott Frendo-Cumbo,Natalie Krahmer,Jiunn Song,Leena Kuruvilla,Chandramohan Chitraju,Sebastian Boland,Dong-Keun Jang,Marcin von Grotthuss,Maria C Costanzo,Mikael Rydén,James A Olzmann,Jason Flannick,Noël P Burtt,Robert V Farese,Tobias C Walther

View all publications

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Abcam Product Promise

我们致力于为您的研究提供高质量的试剂，为您科研的每一步提供支持。若我们的产品未能达到预期性能，我们向您提供 Abcam Product Promise 保障。

详情请参阅我们的条款与条件。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

重组Anti-C16orf45抗体[EPR14087]