AB32385

Anti-c-Jun (phospho S63) 抗体 [Y172]

Name: c-Jun(磷酸化S63)抗体[Y172] (ab32385)| Abcam中文官网
Brand: Abcam Limited
SKU: AB32385
Price: 1521 CNY
Availability: InStock
Rating: 5 (4 reviews)

Anti-c-Jun (phospho S63) antibody [Y172]

20ul selling size
RabMAb
Recombinant
了解详情

(4 Reviews)

(116 Publications)

Anti-c-Jun (phospho S63) antibody [Y172] (ab32385) is a rabbit monoclonal antibody detecting c-Jun in Western Blot, IHC-P, ICC/IF, ELISA, Dot Blot. Suitable for Human, Mouse.

- Biophysical QC for unrivalled batch-batch consistency
- Over 90 publications
- Trusted since 2006

查看别名

Transcription factor Jun, Activator protein 1, Proto-oncogene c-Jun, Transcription factor AP-1 subunit Jun, V-jun avian sarcoma virus 17 oncogene homolog, p39, AP1, JUN

10 Images

Immunocytochemistry/ Immunofluorescence - Anti-c-Jun (phospho S63) antibody [Y172] (AB32385)

ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-c-Jun (phospho S63) antibody [Y172] (AB32385)

Immunofluorescent analysis of 4% paraformaldehyde-fixed, 0.1% Triton X-100 permeabilized A431 (Human epidermoid carcinoma cell line) cells labeling c-Jun (phospho S63) with ab32385 at 1/100 dilution, followed by Goat Anti-Rabbit IgG H&L (Alexa Fluor^® 488) (ab150077) secondary antibody at 1/1000 dilution (green). Confocal image showing the expression was increased after treatment with anisomycin (1 μg/ml for 15 minutes), then decreased after treatment with the Lambda Protein Phosphatase treatment 31℃ for 2 hours. The nuclear counter stain is DAPI (blue).
Counterstained with ab195889 Anti-alpha Tubulin antibody [DM1A] - Microtubule Marker (Alexa Fluor^® 594) at a 1/200 dilution (red).

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-c-Jun (phospho S63) antibody [Y172] (AB32385)

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-c-Jun (phospho S63) antibody [Y172] (AB32385)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of Human breast tissue sections labeling c-Jun with Purified ab32385 at 1 : 250 dilution (0.46 µg/ml). Heat mediated antigen retrieval was performed using using ab93684 (Tris/EDTA buffer, pH 9.0)ImmunoHistoProbe one step HRP Polymer (ready to use)was used as the secondary antibody.Negative control : PBS instead of the primary antibody.Hematoxylinwas used as a counterstain

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-c-Jun (phospho S63) antibody [Y172] (AB32385)

Paraffin-embedded human breast carcinoma tissue stained for c-Jun (phospho S63) with unpurified ab32385 at a 1/50 dilution in immunohistochemical analysis.

ICC/IF

Lab

Immunocytochemistry/ Immunofluorescence - Anti-c-Jun (phospho S63) antibody [Y172] (AB32385)

Immunocytochemistry confocal image of 4% paraformaldehyde-fixed 0.1% Triton X-100 permeabilized anisomycin-treated NIH/3T3 cell line (mouse embryonic fibroblast), staining nuclear c-Jun with ab32385 at 1 : 500 dilution and ab150077 AlexaFluor®488 Goat anti-Rabbit secondary at 1 : 1000 dilution. The counterstain was ab195889 Anti-alpha Tubulin antibody [DM1A] - Microtubule Marker (Alexa Fluor® 594) at 1 : 200 dilution, and the nuclear counterstain was DAPI (blue).

The NIH/3T3 cells were treated with 250 ng/ml Anisomycin for 30 minutes and then the signal decreased after phosphatase treatment at 37°C for 2 hours.

Lab

Western blot - Anti-c-Jun (phospho S63) antibody [Y172] (AB32385)

Blocking and diluting buffer and concentration : 5% NFDM/TBST.

All lanes:

Western blot - Anti-c-Jun (phospho S63) antibody [Y172] (ab32385) at 1/1000 dilution

Lane 1:

HeLa (Human cervix adenocarcinoma epithelial cell) whole cell lysates at 15 µg

Lane 2:

HeLa (Human cervix adenocarcinoma epithelial cell) treated with 1ug/mL anisomycin for 15 minutes whole cell lysates at 15 µg

Lane 3:

HeLa (Human cervix adenocarcinoma epithelial cell) treated with 1ug/ml anisomycin for 15 minutes whole cell lysates. Then the membrane was incubated with phosphatase. at 15 µg

Secondary

All lanes:

Western blot - Goat Anti-Rabbit IgG H&L (HRP) (<a href='/products/secondary-antibodies/goat-rabbit-igg-h-l-hrp-ab97051'>ab97051</a>) at 1/20000 dilution

Predicted band size: 35 kDa

false

Unknown

Western blot - Anti-c-Jun (phospho S63) antibody [Y172] (AB32385)

Blocking and diluting buffer : 5% NFDM/TBST.

This data was developed using the same antibody clone in a different buffer formulation containing PBS, BSA, glycerol, and sodium azide (ab32385).

All lanes:

Western blot - Anti-c-Jun (phospho S63) antibody [Y172] (ab32385) at 0.1 µg/mL

Lane 1:

HeLa (Human cervix adenocarcinoma epithelial cell) whole cell lysates at 15 µg

Lane 2:

HeLa (Human cervix adenocarcinoma epithelial cell) treated with 1 ug/ml anisomycin for 15 minutes whole cell lysates at 15 µg

Lane 3:

HeLa (Human cervix adenocarcinoma epithelial cell) treated with 1 ug/ml anisomycin for 15 minutes whole cell lysates 15ug. Then the membrane was incubated with phosphatase. at 15 µg

Secondary

All lanes:

Western blot - Goat Anti-Rabbit IgG H&L (HRP) (<a href='/products/secondary-antibodies/goat-rabbit-igg-h-l-hrp-ab97051'>ab97051</a>) at 1/20000 dilution

Predicted band size: 35 kDa

false

Unknown

Dot Blot - Anti-c-Jun (phospho S63) antibody [Y172] (AB32385)

Unpurified ab32385 used at a 1 : 1000 dilution.
Secondary antibody is Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated (ab97051) used at a 1 : 100,000 dilution. Blocking/Diluting buffer and concentration : 5% NFDM/TBST.
Lane 1 : Human c-Jun (pS63) phospho peptide.
Lane 2 : Human c-Jun non-phospho peptide.
Exposure time 3 minutes.

Unknown

Western blot - Anti-c-Jun (phospho S63) antibody [Y172] (AB32385)

All lanes:

Western blot - Anti-c-Jun (phospho S63) antibody [Y172] (ab32385) at 1/10000 dilution

Lanes 1 and 3:

Untreated NIH/3T3 (Mouse embyro fibroblast cell line) cell lysate

Lane 2:

NIH/3T3 (Mouse embyro fibroblast cell line) cell lysate treated with ultraviolet light

Lane 4:

NIH/3T3 (Mouse embyro fibroblast cell line) cell lysate treated with 25 µg/ml Anisomycin for 15 minutes at 37°C

Predicted band size: 35 kDa

Observed band size: 42 kDa

false

Unknown

Western blot - Anti-c-Jun (phospho S63) antibody [Y172] (AB32385)

Blocking and diluting buffer : 5% NFDM/TBST.

All lanes:

Western blot - Anti-c-Jun (phospho S63) antibody [Y172] (ab32385) at 0.1 µg/mL

Lane 1:

NIH/3T3 (Mouse embryonic fibroblast) whole cell lysates at 15 µg

Lane 2:

NIH/3T3 (Mouse embryonic fibroblast) treated with 250 ng/ml anisomycin for 30 minutes whole cell lysates at 15 µg

Lane 3:

NIH/3T3 (Mouse embryonic fibroblast) treated with 250 ng/ml anisomycin for 30 minutes whole cell lysates. Then the membrane was incubated with phosphatase at 15 µg

Secondary

All lanes:

Western blot - Goat Anti-Rabbit IgG H&L (HRP) (<a href='/products/secondary-antibodies/goat-rabbit-igg-h-l-hrp-ab97051'>ab97051</a>) at 1/20000 dilution

Predicted band size: 35 kDa

false

ELISA - Anti-c-Jun (phospho S63) antibody [Y172] (AB32385)

ELISA

Unknown

ELISA - Anti-c-Jun (phospho S63) antibody [Y172] (AB32385)

Antigen pS63 : c-Jun (phospho S63); NP : c-Jun non-phospho. Antigen concentration 0.01~1 ng/ml.

Primary antibody concentration range 0~1000 ng/ml.

Secondary antibody is an Alkaline Phosphatase-conjugated Goat Anti-Rabbit IgG(H+L) used at a 1 : 2500 dilution.

不同偶联物与剂型 (7)

617 Alexa Fluor® 594

Alexa Fluor® 594 Anti-c-Jun (phospho S63) antibody [Y172]
603 Alexa Fluor® 568

Alexa Fluor® 568 Anti-c-Jun (phospho S63) antibody [Y172]
Carrier free

Anti-c-Jun (phospho S63) antibody [Y172] - BSA and Azide free
519 Alexa Fluor® 488

Alexa Fluor® 488 Anti-c-Jun (phospho S63) antibody [Y172]
665 Alexa Fluor® 647

Alexa Fluor® 647 Anti-c-Jun (phospho S63) antibody [Y172]
565 Alexa Fluor® 555

Alexa Fluor® 555 Anti-c-Jun (phospho S63) antibody [Y172]
775 Alexa Fluor® 750

Alexa Fluor® 750 Anti-c-Jun (phospho S63) antibody [Y172]

关键信息

宿主种属

Rabbit

克隆

Monoclonal

克隆号

Y172

亚型

IgG

不含载体蛋白

反应种属

Mouse, Human

应用

ICC/IF, WB, ELISA, IHC-P, Dot

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

特异性

Anti-c-Jun (phospho S63) antibody [Y172] (ab32385) only detects c-Jun phosphorylated on Serine 63 when tested in WB and ICC using specific phospho-treatments. However, in DotBlot and ELISA assays we detected some cross-reactivity with the non-phospho peptide as well. Please refer to the images on the datasheet. The mouse recommendation is based on the WB results. We do not guarantee IHC-P for mouse.

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "Dot" : {"fullname" : "Dot Blot", "shortname":"Dot"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/100 - 1/200", "ICCIF-species-notes": "", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "", "Dot-species-checked": "testedAndGuaranteed", "Dot-species-dilution-info": "1/1000", "Dot-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/250", "IHCP-species-notes": "For unpurified use at 1/50 - 1/100The mouse recommendation is based on the WB results. We do not guarantee IHC-P for mouse. Perform heat-mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol." }, "Mouse": { "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/100 - 1/200", "ICCIF-species-notes": "", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "", "Dot-species-checked": "guaranteed", "Dot-species-dilution-info": "", "Dot-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "ELISA-species-checked": "predicted", "ELISA-species-dilution-info": "", "ELISA-species-notes": "", "Dot-species-checked": "predicted", "Dot-species-dilution-info": "", "Dot-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Cow": { "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "ELISA-species-checked": "predicted", "ELISA-species-dilution-info": "", "ELISA-species-notes": "", "Dot-species-checked": "predicted", "Dot-species-dilution-info": "", "Dot-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Recombinant fragment - Human": { "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "ELISA-species-checked": "testedAndGuaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "", "Dot-species-checked": "notRecommended", "Dot-species-dilution-info": "", "Dot-species-notes": "", "WB-species-checked": "notRecommended", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

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产品详情

What is this antibody validated in?
Anti-c-Jun (phospho S63) antibody [Y172] (ab32385) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF), ELISA, Dot Blot in Human, Mouse samples.

What is the molecular weight of c-Jun?
Anti-c-Jun (phospho S63) [Y172] (ab32385) specifically detects a band for c-Jun (UniProt: P05412) at a molecular weight of 36kDa.

Trusted by the scientific community
Anti-c-Jun (phospho S63) [Y172] (ab32385) was first used in a scientific publication in 2006 and has been cited over 90 times in peer-reviewed journals.

Trial sizes available!
Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies.

Other related products
We have a range of other formats of antibody clone [Y172] also available for your convenience: ab32385, Carrier free - ab227533, Alexa Fluor® 488 - ab310948, Alexa Fluor® 647 - ab311066, Alexa Fluor® 594 - ab311651, Alexa Fluor® 568 - ab312924, Alexa Fluor® 555 - ab313136, Alexa Fluor® 750 - ab321597

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

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性能和储存信息

形式

Liquid

纯化工艺

Affinity purification Protein A

存储溶液

pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA

运输条件

Blue Ice

分装信息

Upon delivery aliquot

储存信息

Avoid freeze / thaw cycle

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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

The protein c-Jun is an important component of the AP-1 transcription factor complex and is often referred to by alternative names such as c-jun. It has a molecular weight of about 39 kDa. Scientists have found c-jun expressed in a wide range of tissues indicating its diverse roles in cellular functions. This protein plays a critical mechanical role by binding specific DNA sequences to regulate the transcription of various genes involved in cell proliferation and apoptosis.

Biological function summary

C-Jun impacts cellular activities by being a significant part of the AP-1 transcription factor complex interacting with other proteins such as Fos. This interaction allows c-Jun to modulate gene expression in response to cellular stimuli. In particular c-Jun influences cell cycle progression and differentiation. Therefore its activity is necessary for physiological and pathological processes. As c-jun's function remains tightly regulated any changes can have wide-ranging effects.

Pathways

C-Jun significantly influences the MAPK/ERK and JNK pathways. These pathways play important roles in cellular responses to stress growth factors and cytokines. Within these pathways c-Jun interacts with proteins such as JNK which phosphorylates c-Jun and enhances its activity. These interactions allow c-Jun to regulate target genes involved in important cellular processes without much delay. Understanding c-Jun's function in these pathways helps elucidate how cells control division survival and apoptosis.

C-Jun's dysregulation connects to various conditions including cancer and neurodegenerative diseases. Abnormal c-Jun activity can lead to oncogenesis by promoting unrestrained cellular proliferation. Additionally c-Jun involvement in disorders like Alzheimer's disease stems from its role in apoptotic pathways which may cause neuronal death. Accompanying proteins like JNK are also implicated in these conditions making the regulation and expression of c-Jun a focus for therapeutic research.

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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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靶点信息

Transcription factor that recognizes and binds to the AP-1 consensus motif 5'-TGA[GC]TCA-3' (PubMed : 10995748, PubMed : 22083952). Heterodimerizes with proteins of the FOS family to form an AP-1 transcription complex, thereby enhancing its DNA binding activity to the AP-1 consensus sequence 5'-TGA[GC]TCA-3' and enhancing its transcriptional activity (By similarity). Together with FOSB, plays a role in activation-induced cell death of T cells by binding to the AP-1 promoter site of FASLG/CD95L, and inducing its transcription in response to activation of the TCR/CD3 signaling pathway (PubMed : 12618758). Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation (PubMed : 17210646). Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed : 24623306). Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed : 24623306).. (Microbial infection) Upon Epstein-Barr virus (EBV) infection, binds to viral BZLF1 Z promoter and activates viral BZLF1 expression.

See full target information JUN phospho S63

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文献 (116)

Recent publications for all applications. Explore the full list and refine your search

Nature 644:516-526 PubMed40681898

2025

Pathology-oriented multiplexing enables integrative disease mapping.

Applications

Unspecified application

Species

Unspecified reactive species

Malte Kuehl,Yusuke Okabayashi,Milagros N Wong,Lukas Gernhold,Gabriele Gut,Nico Kaiser,Maria Schwerk,Stefanie K Gräfe,Frank Y Ma,Jovan Tanevski,Philipp S L Schäfer,Sam Mezher,Jacobo Sarabia Del Castillo,Thiago Goldbeck-Strieder,Olga Zolotareva,Michael Hartung,Fernando M Delgado Chaves,Lukas Klinkert,Ann-Christin Gnirck,Marc Spehr,David Fleck,Mehdi Joodaki,Victor Parra,Mina Shaigan,Martin Diebold,Marco Prinz,Jennifer Kranz,Johan M Kux,Fabian Braun,Oliver Kretz,Hui Wu,Florian Grahammer,Sven Heins,Marina Zimmermann,Fabian Haas,Dominik Kylies,Nicola Wanner,Jan Czogalla,Bernhard Dumoulin,Nikolay Zolotarev,Maja Lindenmeyer,Pall Karlson,Jens R Nyengaard,Marcial Sebode,Sören Weidemann,Thorsten Wiech,Hermann-Josef Groene,Nicola M Tomas,Catherine Meyer-Schwesinger,Christoph Kuppe,Rafael Kramann,Alexandre Karras,Patrick Bruneval,Pierre-Louis Tharaux,Diego Pastene,Benito Yard,Jennifer A Schaub,Phillip J McCown,Laura Pyle,Ye Ji Choi,Takashi Yokoo,Jan Baumbach,Pablo J Sáez,Ivan Costa,Jan-Eric Turner,Jeffrey B Hodgin,Julio Saez-Rodriguez,Tobias B Huber,Petter Bjornstad,Matthias Kretzler,Olivia Lenoir,David J Nikolic-Paterson,Lucas Pelkmans,Stefan Bonn,Victor G Puelles

Cell reports. Medicine 6:102000 PubMed40056904

2025

LTA4H improves the tumor microenvironment and prevents HCC progression via targeting the HNRNPA1/LTBP1/TGF-β axis.

Applications

Unspecified application

Species

Unspecified reactive species

Shuai Yang,Xinyao Qiu,Yingcheng Yang,Jing Wu,Shan Wang,Bo Zheng,Jianmin Wu,Tao Zhou,Yangqianwen Zhang,Mixue Bai,Shuowu Liu,Zihan Zhao,Yani Zhang,Yixian Wang,Jinxia Bao,Mengye Wu,Dongdong Xue,Meiyu Bao,Ji Hu,Siyun Shen,Hongyang Wang,Lei Chen

Frontiers in immunology 16:1515605 PubMed39963142

2025

Resveratrol contributes to NK cell-mediated breast cancer cytotoxicity by upregulating ULBP2 through miR-17-5p downmodulation and activation of MINK1/JNK/c-Jun signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Bisha Ding,Jie Li,Jia-Lin Yan,Chun-Yan Jiang,Ling-Bo Qian,Jie Pan

Cellular and molecular life sciences : CMLS 82:45 PubMed39833479

2025

Sirtuin 2 exacerbates renal tubule injury and inflammation in diabetic mice via deacetylation of c-Jun/c-Fos.

Applications

Unspecified application

Species

Unspecified reactive species

Li Chen,Dan Li,Zishun Zhan,Jingjing Quan,Juan Peng,Zhijun Huang,Bin Yi

Journal of cellular and molecular medicine 28:e70237 PubMed39643939

2024

Endothelial KDM5B Regulated by Piezo1 Contributes to Disturbed Flow Induced Atherosclerotic Plaque Formation.

Applications

Unspecified application

Species

Unspecified reactive species

Lili Wu,Shanshan Jiang,Xiao Zhou,Wei Li,Jiaqi Ke,Ziting Liu,Lijie Ren,Qiongyu Lu,Fengchan Li,Chaojun Tang,Li Zhu

The Journal of physiology 602:4959-4985 PubMed39197117

2024

Jun-activated SOCS1 enhances ubiquitination and degradation of CCAAT/enhancer-binding protein β to ameliorate cerebral ischaemia/reperfusion injury.

Applications

Unspecified application

Species

Unspecified reactive species

Chuan He,Tie Wang,Yanwu Han,Changyang Zuo,Guangming Wang

Signal transduction and targeted therapy 9:214 PubMed39117631

2024

Ribosomal modification protein rimK-like family member A activates betaine-homocysteine S-methyltransferase 1 to ameliorate hepatic steatosis.

Applications

Unspecified application

Species

Unspecified reactive species

Han Yan,Wenjun Liu,Rui Xiang,Xin Li,Song Hou,Luzheng Xu,Lin Wang,Dong Zhao,Xingkai Liu,Guoqing Wang,Yujing Chi,Jichun Yang

iScience 27:110286 PubMed39055952

2024

Nuclear enhances the malignant behavior of A549 cells and impacts lung adenocarcinoma patient prognosis.

Applications

Unspecified application

Species

Unspecified reactive species

Mingfang Xu,Yingda Liu,Xunjie Kuang,Yu Pu,Yuzhu Jiang,Xiaodong Zhao,Xueqin Yang,Mengxia Li

Military Medical Research 11:41 PubMed38937853

2024

PANX1-mediated ATP release confers FAM3A's suppression effects on hepatic gluconeogenesis and lipogenesis.

Applications

Unspecified application

Species

Unspecified reactive species

Cheng-Qing Hu,Tao Hou,Rui Xiang,Xin Li,Jing Li,Tian-Tian Wang,Wen-Jun Liu,Song Hou,Di Wang,Qing-He Zhao,Xiao-Xing Yu,Ming Xu,Xing-Kai Liu,Yu-Jing Chi,Ji-Chun Yang

iScience 27:109502 PubMed38591009

2024

CircTMEM165 facilitates endothelial repair by modulating mitochondrial fission via miR-192/SCP2 and .

Applications

Unspecified application

Species

Unspecified reactive species

Yan Liu,Yanyan Yang,Min Li,Xiuxiu Fu,Xiangqin He,Xiaoxin Li,Jae Youl Cho,Pei-Feng Li,Tao Yu

View all publications

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