AB155010

Anti-BNIP3L/NIX 抗体

Name: BNIP3L/NIX抗体 (ab155010)| Abcam中文官网
Brand: Abcam Limited
SKU: AB155010
Price: 4922 CNY
Availability: InStock

Anti-BNIP3L/NIX antibody

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(4 Publications)

Rabbit Polyclonal BNIP3L/NIX antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Mouse, Human samples. Cited in 4 publications. Immunogen corresponding to Synthetic Peptide within Human BNIP3L aa 50-200.

查看别名

BNIP3A, BNIP3H, NIX, BNIP3L, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like, Adenovirus E1B19K-binding protein B5, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A, NIP3-like protein X, NIP3L

2 Images

Immunocytochemistry/ Immunofluorescence - Anti-BNIP3L/NIX antibody (AB155010)

ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-BNIP3L/NIX antibody (AB155010)

Immunofluorescent analysis of methanol-fixed HeLa cells labeling BNIP3L/NIX with ab155010 antibody at 1/200 dilution. Bottom figure : staining merged with DNA probe (Hoechst 33342).

Supplier Data

Western blot - Anti-BNIP3L/NIX antibody (AB155010)

Samples were separated by 10 % SDS.

All lanes:

Western blot - Anti-BNIP3L/NIX antibody (ab155010) at 1/1000 dilution

Lane 1:

Untreated HeLa whole cell extracts at 30 µg

Lane 2:

Treated HeLa whole cell extracts at 30 µg

Secondary

All lanes:

HRP-conjugated anti-rabbit IgG antibody

Predicted band size: 24 kDa

false

关键信息

宿主种属

Rabbit

克隆

Polyclonal

亚型

IgG

不含载体蛋白

反应种属

Mouse, Human

应用

WB, ICC/IF, IHC-P

applications

免疫原

Synthetic Peptide within Human BNIP3L aa 50-200. The exact immunogen used to generate this antibody is proprietary information.

O60238

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "1/100 - 1/1000", "IHCP-species-notes": "", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/100 - 1/1000", "ICCIF-species-notes": "" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Chicken": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Cow": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Monkey": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }

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性能和储存信息

形式

Liquid

纯化工艺

Affinity purification Immunogen

存储溶液

pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 10% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine

运输条件

Blue Ice

分装信息

Upon delivery aliquot

储存信息

Avoid freeze / thaw cycle

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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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靶点信息

Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP : in response to mitochondrial damage, participates in mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. May function as a tumor suppressor.

See full target information BNIP3L

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文献 (4)

Recent publications for all applications. Explore the full list and refine your search

EMBO reports 26:3384-3410 PubMed40437287

2025

KEAP1 retention in phase-separated p62 bodies drives liver damage under autophagy-deficient conditions.

Applications

Unspecified application

Species

Unspecified reactive species

Shuhei Takada,Nozomi Shinomiya,Gaoxin Mao,Hikaru Tsuchiya,Tomoaki Koga,Satoko Komatsu-Hirota,Yu-Shin Sou,Manabu Abe,Elena Ryzhii,Michitaka Suzuki,Mitsuyoshi Nakao,Satoshi Waguri,Hideaki Morishita,Masaaki Komatsu

International journal of molecular sciences 26: PubMed40004139

2025

Proteomics and Expression of HIF2α/BNIP3L Signaling in Yak Brains at Different Altitudes.

Applications

Unspecified application

Species

Unspecified reactive species

Qian Zhang,Yan Cui,Sijiu Yu,Junfeng He,Yangyang Pan,Meng Wang,Jialing Che

Journal of experimental & clinical cancer research : CR 43:273 PubMed39350223

2024

Targeting DNM1L/DRP1-FIS1 axis inhibits high-grade glioma progression by impeding mitochondrial respiratory cristae remodeling.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaodong Li,Jingjing Tie,Yuze Sun,Chengrong Gong,Shizhou Deng,Xiyu Chen,Shujiao Li,Yaoliang Wang,Zhenhua Wang,Feifei Wu,Hui Liu,Yousheng Wu,Guopeng Zhang,Qingdong Guo,Yanling Yang,Yayun Wang

Cell death & disease 11:251 PubMed32312970

2020

Drp1 regulates mitochondrial dysfunction and dysregulated metabolism in ischemic injury via Clec16a-, BAX-, and GSH- pathways.

Applications

Unspecified application

Species

Unspecified reactive species

Chenyang Duan,Lei Kuang,Xinming Xiang,Jie Zhang,Yu Zhu,Yue Wu,Qingguang Yan,Liangming Liu,Tao Li

View all publications

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