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AB244992

重组Anti-BMP4抗体[EPR18235-122] - BSA and Azide free (Detector)

Anti-BMP4 antibody [EPR18235-122] - BSA and Azide free (Detector)

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Rabbit Recombinant Monoclonal BMP4 antibody. Carrier free. Suitable for sELISA and reacts with Human samples.

查看别名

BMP2B, DVR4, BMP4, Bone morphogenetic protein 4, BMP-4, Bone morphogenetic protein 2B, BMP-2B

1 Images
Sandwich ELISA - Anti-BMP4 antibody [EPR18235-122] - BSA and Azide free (Detector) (AB244992)
  • sELISA

Supplier Data

Sandwich ELISA - Anti-BMP4 antibody [EPR18235-122] - BSA and Azide free (Detector) (AB244992)

Representative standard curve from corresponding SimpleStep ELISA® Kit (ab231930).

关键信息

宿主种属

Rabbit

克隆

Monoclonal

克隆号

EPR18235-122

亚型

IgG

不含载体蛋白

Yes

反应种属

Human

应用

sELISA

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

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搭配使用产品

Assay Kits

AB231930

Human BMP-4 ELISA Kit

Recombinant|SimpleStep

ELISA - Human BMP-4 ELISA Kit (AB231930)

  • 0
  • 0
Sample Prep & Detection Kits

AB201799

DyLight® 488 Conjugation Kit (Fast) - Lightning-Link®

Flow Cytometry - DyLight® 488 Conjugation Kit (Fast) - Lightning-Link® (AB201799)

  • 5
  • 1
Sample Prep & Detection Kits

AB186922

Biotin Gold Conjugate (40nm, 10 OD)

Functional Studies - Biotin Gold Conjugate (40nm, 10 OD) (AB186922)

  • 0
  • 0
Primary Antibodies

AB300185

Anti-Cofilin-1 antibody [EPR24514-8] - BSA and Azide free (Detector)

BOND RX™ Validated|RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Anti-Cofilin-1 antibody [EPR24514-8] - BSA and Azide free (Detector) (AB300185)

  • 0
  • 0
Primary Antibodies

AB281555

Anti-Fatty Acid Synthase antibody [EPR22980-236] - BSA and Azide free (Detector)

RabMAb|Recombinant

Sandwich ELISA - Anti-Fatty Acid Synthase antibody [EPR22980-236] - BSA and Azide free (Detector) (AB281555)

  • 0
  • 0
Primary Antibodies

AB285036

Anti-ETS1 antibody [EPR24021-102] - BSA and Azide free (Capture)

RabMAb|Recombinant

Sandwich ELISA - Anti-ETS1 antibody [EPR24021-102] - BSA and Azide free (Capture) (AB285036)

  • 0
  • 0
Primary Antibodies

AB302564

Anti-CD161 antibody [EPR26340-6]

BOND RX™ Validated|20ul selling size|RabMAb|Advanced Validation|Recombinant

Multiplex immunohistochemistry - Anti-CD161 antibody [EPR26340-6] (AB302564)

  • 4
  • 1
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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "sELISA" : {"fullname" : "Sandwich ELISA", "shortname":"sELISA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "sELISA-species-checked": "guaranteed", "sELISA-species-dilution-info": "", "sELISA-species-notes": "<p></p>" } } }
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产品详情

ab244992 is a BSA and Azide Free antibody supplied in an unconjugated format and it is suitable for sandwich ELISAs to quantify Human BMP-4. The recommended pair for sandwich ELISA is:
Capture: ab244725, Human BMP-4 Capture Antibody (unconjugated)
Detector: ab244992, Human BMP-4 Detector Antibody (unconjugated)
The reference range value is 12 - 750 pg/ml.

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.

Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

Sandwich ELISA
The recommended antibody orientation is based on internal optimization for ELISA-based assays. Antibody orientation is assay dependent and needs to be optimized for each assay type. Please note that the range provided for this antibody is only an estimation based on the performance of the product using the recommended antibody pair. Performance of the antibody pair will depend on the specific characteristics of your assay. We guarantee the product works in sandwich ELISA, but we do not guarantee the sensitivity or dynamic range of the antibody in your assay.

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性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Protein A
存储溶液
Constituents: PBS
运输条件
Blue Ice
推荐的短期储存条件
+4°C
推荐的长期储存条件
+4°C
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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:
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靶点信息

Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including neurogenesis, vascular development, angiogenesis and osteogenesis (PubMed : 31363885). Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity). Initiates the canonical BMP signaling cascade by associating with type I receptor BMPR1A and type II receptor BMPR2 (PubMed : 25868050, PubMed : 8006002). Once all three components are bound together in a complex at the cell surface, BMPR2 phosphorylates and activates BMPR1A. In turn, BMPR1A propagates signal by phosphorylating SMAD1/5/8 that travel to the nucleus and act as activators and repressors of transcription of target genes (PubMed : 25868050, PubMed : 29212066). Positively regulates the expression of odontogenic development regulator MSX1 via inducing the IPO7-mediated import of SMAD1 to the nucleus (By similarity). Required for MSX1-mediated mesenchymal molar tooth bud development beyond the bud stage, via promoting Wnt signaling (By similarity). Acts as a positive regulator of odontoblast differentiation during mesenchymal tooth germ formation, expression is repressed during the bell stage by MSX1-mediated inhibition of CTNNB1 signaling (By similarity). Able to induce its own expression in dental mesenchymal cells and also in the neighboring dental epithelial cells via an MSX1-mediated pathway (By similarity). Can also signal through non-canonical BMP pathways such as ERK/MAP kinase, PI3K/Akt, or SRC cascades (PubMed : 31363885). For example, induces SRC phosphorylation which, in turn, activates VEGFR2, leading to an angiogenic response (PubMed : 31363885).
See full target information BMP4
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Abcam Product Promise

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详情请参阅我们的条款与条件。

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