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AB278566

重组Anti-BLNK (phospho Y84)抗体[BLNKY84-H4]

Anti-BLNK (phospho Y84) antibody [BLNKY84-H4]

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(1 Publication)

Rabbit Recombinant Monoclonal BLNK phospho Y84 antibody. Suitable for Flow Cyt and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human BLNK phospho Y84.

查看别名

BASH, SLP65, BLNK, B-cell linker protein, B-cell adapter containing a SH2 domain protein, B-cell adapter containing a Src homology 2 domain protein, Cytoplasmic adapter protein, Src homology 2 domain-containing leukocyte protein of 65 kDa, SLP-65

3 Images
Flow Cytometry - Anti-BLNK (phospho Y84) antibody [BLNKY84-H4] (AB278566)
  • Flow Cyt

Supplier Data

Flow Cytometry - Anti-BLNK (phospho Y84) antibody [BLNKY84-H4] (AB278566)

Flow cytometric analysis of Daudi cells secondary antibody only negative control (blue) or untreated (red) or treated with IFNa + IL-4 + pervanadate (green) using ab278566 at 0.01 µg/mL.

Flow Cytometry - Anti-BLNK (phospho Y84) antibody [BLNKY84-H4] (AB278566)
  • Flow Cyt

Supplier Data

Flow Cytometry - Anti-BLNK (phospho Y84) antibody [BLNKY84-H4] (AB278566)

Flow cytometric analysis of Daudi cells secondary antibody only negative control (blue) or untreated (red) or treated with IFNa + IL-4 + pervanadate (green) using 10 ng/mL of ab278566.

Flow Cytometry - Anti-BLNK (phospho Y84) antibody [BLNKY84-H4] (AB278566)
  • Flow Cyt

Supplier Data

Flow Cytometry - Anti-BLNK (phospho Y84) antibody [BLNKY84-H4] (AB278566)

Peptide blocking flow cytometric analysis of Daudi cells secondary antibody only negative control (light blue) or untreated (red) or with IFNa + IL-4 + pervanadate (green) or untreated and blocked with phospho-peptide (black) or treated and blocked with phospho peptide (gold) or untreated and blocked with non-phospho peptide (dark blue) or treated and blocked with non-phospho peptide (purple) using ab278566 at 0.01 µg/mL.

关键信息

宿主种属

Rabbit

克隆

Monoclonal

克隆号

BLNKY84-H4

亚型

IgG

轻链类型

kappa

不含载体蛋白

No

反应种属

Human

应用

Flow Cyt

applications

免疫原

Synthetic Peptide within Human BLNK phospho Y84. The exact immunogen used to generate this antibody is proprietary information.

Q8WV28

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "0.001-1 µg/mL", "FlowCyt-species-notes": "<p></p>" } } }
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产品详情

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

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性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Protein A/G
存储溶液
Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.1% BSA
运输条件
Blue Ice
推荐的短期储存时间
1-2 weeks
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle
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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:
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靶点信息

Functions as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR-mediated PLCG1 and PLCG2 activation and Ca(2+) mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR-mediated activation of MAP kinase and phosphatidyl-inositol 3 (PI3) kinase signaling. May be required for the RAC1-JNK pathway. Plays a critical role in orchestrating the pro-B cell to pre-B cell transition. May play an important role in BCR-induced B-cell apoptosis.
See full target information BLNK phospho Y84
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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in pharmacology 15:1284752 PubMed38860166

2024

- herb pair in the progression of hepatitis, cirrhosis, and hepatocellular carcinoma: a possible mechanisms and relevant therapeutic substances.

Applications

Unspecified application

Species

Unspecified reactive species

Xiao Yang,Chen Liang,Li Shao,Wenxuan Cui,Ruobing Ning,Fan Ke,Yue Wang,Peng Gao,Yidi Yin,Qing Li
View all publications
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