生物素Anti-Urokinase抗体(ab49577)
Key features and details
- Biotin Rabbit polyclonal to Urokinase
- Suitable for: ELISA, IP, RIA, WB
- Reacts with: Human
- Conjugation: Biotin
- Isotype: IgG
概述
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产品名称
生物素Anti-Urokinase抗体
参阅全部 Urokinase 一抗 -
描述
生物素兔多克隆抗体to Urokinase -
宿主
Rabbit -
偶联物
Biotin -
经测试应用
适用于: ELISA, IP, RIA, WBmore details -
种属反应性
与反应: Human -
免疫原
Full length native ATF uPA purified from plasma (Human)
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常规说明
ATF is the amino terminal fragment of urokinase (uPA) corresponding to amino acid residues 1-135. uPA-ATF contains the growth factor like domain, which binds to the urokinase receptor, and the kringle domain which is involved in the induction of cell chemotaxis by urokinase. ATF inhibits the binding of urokinase to its receptor uPAR and acts as a broad inhibitor of cell migration.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.50
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: PBS, 50% Glycerol -
Concentration information loading...
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纯度
Protein G purified -
Primary antibody说明
ATF is the amino terminal fragment of urokinase (uPA) corresponding to amino acid residues 1-135. uPA-ATF contains the growth factor like domain, which binds to the urokinase receptor, and the kringle domain which is involved in the induction of cell chemotaxis by urokinase. ATF inhibits the binding of urokinase to its receptor uPAR and acts as a broad inhibitor of cell migration. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab49577于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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ELISA |
Use at an assay dependent concentration.
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IP |
Use at an assay dependent concentration.
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RIA |
Use at an assay dependent concentration.
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WB |
Use at an assay dependent concentration.
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说明 |
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ELISA
Use at an assay dependent concentration. |
IP
Use at an assay dependent concentration. |
RIA
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. |
靶标
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功能
Specifically cleave the zymogen plasminogen to form the active enzyme plasmin. -
组织特异性
Expressed in the prostate gland and prostate cancers. -
序列相似性
Belongs to the peptidase S1 family.
Contains 1 EGF-like domain.
Contains 1 kringle domain.
Contains 1 peptidase S1 domain. -
翻译后修饰
Phosphorylation of Ser-158 and Ser-323 abolishes proadhesive ability but does not interfere with receptor binding. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 5328 Human
- Omim: 191840 Human
- SwissProt: P00749 Human
- Unigene: 77274 Human
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别名
- ATF antibody
- ATF uPA antibody
- BDPLT5 antibody
see all
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab49577 尚未被引用在任何文献中。