生物素Anti-HIV1 tat抗体(ab43015)
Key features and details
- Biotin Rabbit polyclonal to HIV1 tat
- Suitable for: WB, ELISA, Flow Cyt
- Reacts with: Human immunodeficiency virus
- Conjugation: Biotin
- Isotype: IgG
概述
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产品名称
生物素Anti-HIV1 tat抗体
参阅全部 HIV1 tat 一抗 -
描述
生物素兔多克隆抗体to HIV1 tat -
宿主
Rabbit -
偶联物
Biotin -
经测试应用
适用于: WB, ELISA, Flow Cytmore details -
种属反应性
与反应: Human immunodeficiency virus -
免疫原
Recombinant full length protein expressed in E. coli
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.40
Constituents: PBS, 0.05% Glycerol -
Concentration information loading...
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纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab43015于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB | ||
ELISA | ||
Flow Cyt |
说明 |
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Flow Cyt: 1/200. Use Streptavidin-FITC conjugated detection reagent.
WB: 1/1000. Predicted molecular weight: 14 kDa. Use Streptavidin (HRP) conjugated detection reagent.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
靶标
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相关性
HIV1 tat (Transactivator of Transcription) protein is a pleiotropic factor that induces a broad range of biological effects in numerous cell types. At the HIV promoter, tat is a powerful transactivator of gene expression which acts by inducing chromatin remodeling and by recruiting elongation-competent transcriptional complexes on to the viral LTR. -
细胞定位
Nuclear. Upon stimulation with EDN1, it is exported from the nucleus to the perinuclear region. -
数据库链接
- Entrez Gene: 155871 Human immunodeficiency virus
- SwissProt: P04608 Human immunodeficiency virus
- SwissProt: P04610 Human immunodeficiency virus
- SwissProt: Q6UFJ9 Human immunodeficiency virus
- SwissProt: Q900K4 Human immunodeficiency virus
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别名
- p14 antibody
- Protein Tat antibody
- Transactivating regulatory protein antibody
数据表及文件
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Datasheet download
文献 (3)
ab43015 被引用在 3 文献中.
- Swamy G et al. IL-1Ra deficiency accelerates intervertebral disc degeneration in C57BL6J mice. JOR Spine 5:e1201 (2022). PubMed: 35783913
- Dickens AM et al. Chronic low-level expression of HIV-1 Tat promotes a neurodegenerative phenotype with aging. Sci Rep 7:7748 (2017). ELISA . PubMed: 28798382
- Johnson TP et al. Induction of IL-17 and nonclassical T-cell activation by HIV-Tat protein. Proc Natl Acad Sci U S A 110:13588-93 (2013). PubMed: 23898208