生物素Anti-Gastrin抗体(ab48283)
Key features and details
- Biotin Rabbit polyclonal to Gastrin
- Suitable for: ELISA
- Reacts with: Human
- Conjugation: Biotin
- Isotype: IgG
概述
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产品名称
生物素Anti-Gastrin抗体
参阅全部 Gastrin 一抗 -
描述
生物素兔多克隆抗体to Gastrin -
宿主
Rabbit -
偶联物
Biotin -
经测试应用
适用于: ELISAmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Sheep, Goat, Horse, Guinea pig, Cow, Cat, Dog, Pig, Rhesus monkey -
免疫原
Synthetic peptide: QGPWLEEEEEAYGWMDF-NH2 conjugated to KLH via carboxyl group, corresponding to amino acids 76-92 of Human Gastrin.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.50
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: PBS, 50% Glycerol -
Concentration information loading...
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纯度
Protein G purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab48283于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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ELISA |
Use at an assay dependent concentration.
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说明 |
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ELISA
Use at an assay dependent concentration. |
靶标
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功能
Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine. -
序列相似性
Belongs to the gastrin/cholecystokinin family. -
翻译后修饰
Two different processing pathways probably exist in antral G-cells. In the dominant pathway progastrin is cleaved at three sites resulting in two major bioactive gastrins, gastrin-34 and gastrin-17. In the putative alternative pathway, progastrin may be processed only at the most C-terminal dibasic site resulting in the synthesis of gastrin-71.
Sulfation enhances proteolytic processing, and blocks peptide degradation. Levels of sulfation differ between proteolytically-cleaved gastrins. Thus, gastrin-6 is almost 73% sulfated, whereas the larger gastrins are less than 50% sulfated. Sulfation levels are also tissue-specific. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 280800 Cow
- Entrez Gene: 2520 Human
- Entrez Gene: 14459 Mouse
- Entrez Gene: 445524 Pig
- Omim: 137250 Human
- SwissProt: P01354 Cat
- SwissProt: P01352 Cow
- SwissProt: P01353 Dog
see all -
别名
- Component II antibody
- G14 antibody
- G17 antibody
see all
数据表及文件
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SDS download
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Datasheet download
文献 (0)
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