AB25285

生物素Anti-CD90 / Thy1抗体[G7]

Name: Biotin Anti-CD90 / Thy1抗体[G7] (ab25285)| Abcam中文官网
Brand: Abcam Limited
SKU: AB25285
Price: 4885 CNY
Availability: InStock

Biotin Anti-CD90 / Thy1 antibody [G7]

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(3 Publications)

Rat Monoclonal CD90 / Thy1 antibody - conjugated to Biotin. Suitable for Flow Cyt and reacts with Mouse samples. Cited in 3 publications.

查看别名

CD90, Thy-1 membrane glycoprotein, CDw90, Thy-1 antigen, THY1

1 Images

Flow Cytometry - Biotin Anti-CD90 / Thy1 antibody [G7] (AB25285)

Flow Cyt

Unknown

Flow Cytometry - Biotin Anti-CD90 / Thy1 antibody [G7] (AB25285)

Flow cytometry analysis of BALB/c mouse splenocytes stained with Rat Anti-Mouse CD90 ab25285 (0.3 µg/10⁶cells) and Rat Anti-Mouse CD3 epsilon-PE ab136222 followed by Streptavidin-FITC.

不同偶联物与剂型 (4)

660 APC

APC Anti-CD90 / Thy1 antibody [G7]
519 FITC

FITC Anti-CD90 / Thy1 antibody [G7]
578 PE

PE Anti-CD90 / Thy1 antibody [G7]
667 PE/Cy5®

PE/Cy5® Anti-CD90 / Thy1 antibody [G7]

关键信息

宿主种属

Rat

克隆

Monoclonal

克隆号

亚型

IgG2c

轻链类型

kappa

偶联物

Biotin

激发波长/发射波长

不含载体蛋白

反应种属

Mouse

应用

Flow Cyt

applications

表位

Thy-1 epitope region A.

特异性

ab25285 recognises Thy-1.1 and Thy-1.2 alloantigens.

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "1 µg for 10^6 Cells", "FlowCyt-species-notes": "<p><a href='/products/unavailable/rat-igg2c-kappa-monoclonal-rtk4174-biotin-isotype-control-ab18543'>ab18543</a> - Rat monoclonal IgG2c, is suitable for use as an isotype control with this antibody.</p>" } } }

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产品详情

ab25285 has been reported to promote apoptosis of thymocytes and CTL clones, and to mediate adhesion of thymocytes to thymic stroma.

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性能和储存信息

形式

Liquid

纯化工艺

Affinity purification

存储溶液

pH: 7.4 Preservative: 0.1% Sodium azide Constituents: PBS

运输条件

Blue Ice

分装信息

Upon delivery aliquot

储存信息

Avoid freeze / thaw cycle

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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

CD90 also known as Thy1 is a glycoprotein with a molecular mass of approximately 25-37 kDa. It is highly conserved across species and found on the surface of various cell types including fibroblasts neurons and endothelial cells. CD90 is expressed in these cells in tissues such as the brain thymus and lungs. Researchers use anti-CD90 antibodies for detection often in combination with CD90 FITC in immunofluorescence assays. CD90 serves as a useful cell marker particularly in identifying mesenchymal stem cells (MSCs).

Biological function summary

CD90 plays a role in cell-cell and cell-matrix interactions contributing to cellular adhesion migration and signal transduction. It functions as part of a complex involving integrins which mediate its interaction with the extracellular matrix. This protein also influences T-cell activation reflecting its importance in immune response regulation. Its presence aids in modulating response to injury and promoting tissue repair due to its association with stem and progenitor cells.

Pathways

CD90 engagement affects focal adhesion and MAPK signaling pathways. It interacts with integrins like αvβ3 and α5β1 influencing cell movement and proliferation processes. CD90 involvement in these pathways allows it to regulate responses important for cell survival and communication within various tissues. These interactions highlight the protein's role in maintaining cellular homeostasis and regulating physiological processes.

CD90 has associations with fibrosis and cancer. In fibrotic conditions CD90 expression affects fibroblast activity influencing tissue scarring in organs such as the liver and lungs. In cancer CD90 modifies tumor progression and metastasis by impacting cell adhesion and migration with connections to proteins like TGF-beta which further drive these processes. Understanding CD90 in disease contexts facilitates the development of therapeutic strategies aimed at modulating its activity.

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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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靶点信息

May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.

See full target information THY1

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文献 (3)

Recent publications for all applications. Explore the full list and refine your search

Journal of clinical medicine 14: PubMed40806966

2025

Effects of a ROCK Inhibitor on Retinal Ganglion Cells In Vivo and In Vitro.

Applications

Unspecified application

Species

Unspecified reactive species

Wanjing Chen,Yoko Iizuka,Fumihiko Mabuchi,Kenji Kashiwagi

Nature communications 9:948 PubMed29507342

2018

Cancer-associated fibroblasts induce antigen-specific deletion of CD8 T Cells to protect tumour cells.

Applications

Unspecified application

Species

Unspecified reactive species

Matthew A Lakins,Ehsan Ghorani,Hafsa Munir,Carla P Martins,Jacqueline D Shields

The Journal of experimental medicine 159:716-30 PubMed6142077

1984

T cell-activating properties of an anti-Thy-1 monoclonal antibody. Possible analogy to OKT3/Leu-4.

Applications

Unspecified application

Species

Unspecified reactive species

K C Gunter,T R Malek,E M Shevach

View all publications

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生物素Anti-CD90 / Thy1抗体[G7]