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Cardiovascular Blood Other

生物素Anti-CD62L抗体[MEL-14] (ab24969)

  • Datasheet
  • SDS
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Key features and details

  • Biotin Rat monoclonal [MEL-14] to CD62L
  • Conjugation: Biotin
  • Isotype: IgG2a

Conjugates logo Related conjugates and formulations

APC Carrier Free FITC PE/Cy7® redFluor™ 710 Unconjugated

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概述

  • 产品名称

    生物素Anti-CD62L抗体[MEL-14]
    参阅全部 CD62L 一抗
  • 描述

    生物素大鼠单克隆抗体[MEL-14] to CD62L
  • 宿主

    Rat
  • 偶联物

    Biotin
  • 免疫原

    Tissue, cells or virus corresponding to Mouse CD62L.
    Database link: 20343

  • 常规说明


    The monoclonal antibody MEL-14 blocks in vitro binding of lymphocytes to peripheral lymph node HEV and inhibits in vivo lymphocyte extravasation into peripheral lymph nodes and the late stages of leukocyte rolling.

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

性能

  • 形式

    Liquid
  • 存放说明

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液

    pH: 7.20
    Preservative: 0.09% Sodium azide
    Constituents: 0.14% Monobasic dihydrogen sodium phosphate, 0.87% Sodium chloride
  • Concentration information loading...
  • 纯度

    Affinity purified
  • Primary antibody说明

    The monoclonal antibody MEL-14 blocks in vitro binding of lymphocytes to peripheral lymph node HEV and inhibits in vivo lymphocyte extravasation into peripheral lymph nodes and the late stages of leukocyte rolling.
  • 克隆

    单克隆
  • 克隆编号

    MEL-14
  • 同种型

    IgG2a
  • 轻链类型

    kappa
  • 研究领域

    • Cardiovascular
    • Blood
    • Other
    • Immunology
    • Adaptive Immunity
    • T Cells
    • CD
    • Stem Cells
    • Hematopoietic Progenitors
    • Lymphoid
    • T Lymphocytic Lineage
    • Stem Cells
    • Hematopoietic Progenitors
    • Myeloid
    • Neutrophil Lineage
    • Immunology
    • Adaptive Immunity
    • Regulatory T Cells

相关产品

  • Alternative Versions

    • Anti-CD62L antibody [MEL-14] (ab119834)
    • redFluor™ 710 Anti-CD62L antibody [MEL-14] (ab242077)
    • FITC Anti-CD62L antibody [MEL-14] (ab24876)
    • PE/Cy7® Anti-CD62L antibody [MEL-14] (ab25569)
    • Anti-CD62L antibody [MEL-14] - BSA and Azide free (ab256147)
    • APC Anti-CD62L antibody [MEL-14] (ab41459)
  • Isotype control

    • Biotin Rat IgG2a, kappa monoclonal [RTK2758] - Isotype Control (ab18445)
  • Recombinant Protein

    • Recombinant Human CD62L protein (ab132972)

靶标

  • 功能

    Cell surface adhesion protein. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia.
  • 组织特异性

    Expressed in B cell lines and T lymphocytes.
  • 序列相似性

    Belongs to the selectin/LECAM family.
    Contains 1 C-type lectin domain.
    Contains 1 EGF-like domain.
    Contains 2 Sushi (CCP/SCR) domains.
  • 细胞定位

    Membrane.
  • Target information above from: UniProt accession P14151 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • 别名

    • A.11 antibody
    • AI528707 antibody
    • CD62 antigen ligand antibody
    • CD62 antigen-like family member L antibody
    • CD62L antibody
    • gp90-MEL antibody
    • IgA nephropathy, susceptibility to, included antibody
    • L Selectin antibody
    • L-selectin antibody
    • LAM-1 antibody
    • LAM1 antibody
    • LECAM1 antibody
    • LEU8 antibody
    • Leukocyte adhesion molecule 1 antibody
    • Leukocyte surface antigen Leu-8 antibody
    • Leukocyte-endothelial cell adhesion molecule 1 antibody
    • Lnhr antibody
    • LSEL antibody
    • Ly-22 antibody
    • Ly-m22 antibody
    • Lyam-1 antibody
    • LYAM1 antibody
    • LYAM1_HUMAN antibody
    • Lymph node homing receptor antibody
    • Lymphocyte adhesion molecule 1 antibody
    • Lymphocyte antigen 22 antibody
    • Lymphocyte surface MEL-14 antigen antibody
    • MEL-14 antibody
    • Pln homing receptor antibody
    • PLNHR antibody
    • Selectin L antibody
    • Selectin, lymphocyte antibody
    • SELL antibody
    • TQ1 antibody
    see all

实验方案

  • Flow cytometry protocols
  • Immunohistochemistry protocols

Click here to view the general protocols

数据表及文件

  • SDS download

  • Datasheet download

    Download

文献 (0)

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