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AB218748

生物素Anti-CD44抗体[IM7]

Biotin Anti-CD44 antibody [IM7]

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(1 Publication)

Rat Monoclonal CD44 antibody - conjugated to Biotin. Suitable for Flow Cyt and reacts with Mouse samples. Cited in 1 publication.

查看别名

CD44, Ly-24, Cd44, CD44 antigen, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Hermes antigen, Hyaluronate receptor, Lymphocyte antigen 24, Phagocytic glycoprotein 1, Phagocytic glycoprotein I, ECMR-III, PGP-1, PGP-I

1 Images
Flow Cytometry - Biotin Anti-CD44 antibody [IM7] (AB218748)
  • Flow Cyt

Supplier Data

Flow Cytometry - Biotin Anti-CD44 antibody [IM7] (AB218748)

Flow cytometry analysis of mouse C57BI/6 splenocytes with 0.5 μg ab218748 (solid line) compared with 0.5 μg rat IgG2b Biotin isotype control (dashed line).

关键信息

宿主种属

Rat

克隆

Monoclonal

克隆号

IM7

亚型

IgG2b

轻链类型

kappa

偶联物

Biotin

激发波长/发射波长
不含载体蛋白

No

反应种属

Mouse

应用

Flow Cyt

applications

特异性

ab218748 may be used for detection of all isoforms of CD44, as it recognizes constant epitopes near the extracellular proximal domain.

反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p>Use 0.5 μg.</p>" } } }

性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Protein A
纯化说明
ab218748 was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.
存储溶液
pH: 7.2 Preservative: 0.09% Sodium azide Constituents: 0.87% Sodium chloride, 0.12% Sodium dihydrogen phosphate, 0.1% Gelatin
运输条件
Blue Ice
推荐的短期储存时间
1-2 weeks
推荐的短期储存条件
+4°C
推荐的长期储存条件
+4°C
分装信息
Upon delivery aliquot
储存信息
Do Not Freeze|Store in the dark

产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

靶点信息

Cell-surface receptor that plays a role in cell-cell interactions, cell adhesion and migration, helping them to sense and respond to changes in the tissue microenvironment. Participates thereby in a wide variety of cellular functions including the activation, recirculation and homing of T-lymphocytes, hematopoiesis, inflammation and response to bacterial infection. Engages, through its ectodomain, extracellular matrix components such as hyaluronan/HA, collagen, growth factors, cytokines or proteases and serves as a platform for signal transduction by assembling, via its cytoplasmic domain, protein complexes containing receptor kinases and membrane proteases (PubMed : 25065622, PubMed : 8343954). Such effectors include PKN2, the RhoGTPases RAC1 and RHOA, Rho-kinases and phospholipase C that coordinate signaling pathways promoting calcium mobilization and actin-mediated cytoskeleton reorganization essential for cell migration and adhesion (By similarity).
See full target information Cd44

文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Journal of virology 88:14040-9 PubMed25253356

2014

Type I interferon signaling enhances CD8+ T cell effector function and differentiation during murine gammaherpesvirus 68 infection.

Applications

Unspecified application

Species

Unspecified reactive species

Ryan N Jennings,Jason M Grayson,Erik S Barton
View all publications

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