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AB95727

生物素Anti-CD41抗体[MW Reg 30]

Biotin Anti-CD41 antibody [MWReg30]

4

(1 Review)

|

(2 Publications)

Rat Monoclonal CD41 antibody - conjugated to Biotin. Suitable for Flow Cyt and reacts with Mouse samples. Cited in 2 publications. Immunogen corresponding to Cell preparation containing Itga2b protein.

查看别名

CD41, Integrin alpha-IIb, GPalpha IIb, Platelet membrane glycoprotein IIb, GPIIb, Itga2b

1 Images
Flow Cytometry - Biotin Anti-CD41 antibody [MWReg30] (AB95727)
  • Flow Cyt

Unknown

Flow Cytometry - Biotin Anti-CD41 antibody [MWReg30] (AB95727)

Mouse platelets stained with 0.06 μg of ab95727 followed by Streptavidin PE.

关键信息

宿主种属

Rat

克隆

Monoclonal

克隆号

MWReg30

亚型

IgG1

轻链类型

kappa

偶联物

Biotin

激发波长/发射波长
不含载体蛋白

No

反应种属

Mouse

应用

Flow Cyt

applications

免疫原

Cell preparation containing Itga2b protein. The exact immunogen used to generate this antibody is proprietary information.

Q9QUM0

反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "0.125 µL for 10^5-10^8 Cells", "FlowCyt-species-notes": "<p>(based on a final test voulme of 100 μl)</p><p><a href='/products/primary-antibodies/biotin-rat-igg1-kappa-rtk2071-isotype-control-ab18403'>ab18403</a> - Rat monoclonal IgG1, is suitable for use as an isotype control with this antibody.</p>" } } }

性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Protein G
存储溶液
pH: 7.2 Preservative: 0.09% Sodium azide Constituents: PBS
运输条件
Blue Ice
推荐的短期储存时间
1-2 weeks
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
储存信息
Avoid freeze / thaw cycle

产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

靶点信息

Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.
See full target information Itga2b

文献 (2)

Recent publications for all applications. Explore the full list and refine your search

Aging 15:630-649 PubMed36734880

2023

Immune-mediated platelet depletion augments Alzheimer's disease neuropathological hallmarks in APP-PS1 mice.

Applications

Unspecified application

Species

Unspecified reactive species

Diana M Bessa de Sousa,Ariane Benedetti,Barbara Altendorfer,Heike Mrowetz,Michael S Unger,Katharina Schallmoser,Ludwig Aigner,Kathrin Maria Kniewallner

Blood 94:684-93 PubMed10397735

1999

Acute systemic reaction and lung alterations induced by an antiplatelet integrin gpIIb/IIIa antibody in mice.

Applications

Unspecified application

Species

Unspecified reactive species

B Nieswandt,B Echtenacher,F P Wachs,J Schröder,J E Gessner,R E Schmidt,G E Grau,D N Männel
View all publications

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