生物素Anti-CD11c抗体[N418] (ab95765)
![Flow Cytometry - Biotin Anti-CD11c antibody [N418] (ab95765)](https://www.abcam.cn/ps/products/95/ab95765/Images/ab95765-277195-anti-cd11c-antibody-n418-biotin-flow-cytometry.jpg "Flow Cytometry - Biotin Anti-CD11c antibody [N418] (ab95765)")
Key features and details
- Biotin Armenian hamster monoclonal [N418] to CD11c
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: Biotin
- Isotype: IgG
Related conjugates and formulations
概述
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产品名称
生物素Anti-CD11c抗体[N418]
参阅全部 CD11c 一抗 -
描述
生物素亚美尼亚仓鼠单克隆抗体[N418] to CD11c -
宿主
Armenian hamster -
偶联物
Biotin -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Mouse -
免疫原
Tissue, cells or virus corresponding to Mouse CD11c. Mouse spleen dendritic cells
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阳性对照
- Flow Cyt: C57BL/6 splenocytes.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. Do Not Freeze. Store In the Dark. -
存储溶液
pH: 7.20
Preservative: 0.09% Sodium azide
Constituents: 0.88% Sodium chloride, 0.1% Gelatin, 0.12% Monobasic dihydrogen sodium phosphate -
Concentration information loading... -
纯度
Affinity purified -
克隆
单克隆 -
克隆编号
N418 -
同种型
IgG -
研究领域
相关产品
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Alternative Versions
- PerCP/Cy5.5® Anti-CD11c antibody [N418] (ab111469)
- Anti-CD11c antibody [N418] - Low endotoxin, Azide free (ab185783)
- APC Anti-CD11c antibody [N418] (ab210306)
- APC/Cy7® Anti-CD11c antibody [N418] (ab210307)
- FITC Anti-CD11c antibody [N418] (ab210308)
- PE Anti-CD11c antibody [N418] (ab210309)
- PE/Cy7® Anti-CD11c antibody [N418] (ab210310)
- Alexa Fluor® 647 Anti-CD11c antibody [N418] (ab233046)
- Anti-CD11c antibody [N418] - BSA and Azide free (ab233173)
- violetFluor™ 450 Anti-CD11c antibody [N418] (ab242269)
- Anti-CD11c antibody [N418] (ab33483)
- Alexa Fluor® 488 Anti-CD11c antibody [N418] (ab33503)
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab95765于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| Flow Cyt |
Use 0.25-0.5µg for 105-8 cells.
Final volume of 100 µl. |
| 说明 |
|---|
|
Flow Cyt
Use 0.25-0.5µg for 105-8 cells. Final volume of 100 µl. |
靶标
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功能
Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. -
组织特异性
Predominantly expressed in monocytes and granulocytes. -
序列相似性
Belongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats.
Contains 1 VWFA domain. -
结构域
The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 16411 Mouse
- SwissProt: Q9QXH4 Mouse
- Unigene: 22378 Mouse
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别名
- 95 alpha chain antibody
- 95 antibody
- CD 11c antibody
see all
图片
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Flow Cytometry - Biotin Anti-CD11c antibody [N418] (ab95765)
C57Bl/6 splenocytes were stained with APC-conjugated anti-MHC CLass II and 0.03µg ab95765 (right) or 0.03µg biotin-conjugated armenian hamster IgG isotype control (left), followed by streptavidin PE.
数据表及文件
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Datasheet download
文献 (8)
ab95765 被引用在 8 文献中.
- Xin KQ et al. Induction of robust immune responses against human immunodeficiency virus is supported by the inherent tropism of adeno-associated virus type 5 for dendritic cells. J Virol 80:11899-910 (2006). PubMed: 17005662
- Ohteki T et al. Essential roles of DC-derived IL-15 as a mediator of inflammatory responses in vivo. J Exp Med 203:2329-38 (2006). PubMed: 16966429
- Zhang J et al. The existence of CD11c+ sentinel and F4/80+ interstitial dendritic cells in dental pulp and their dynamics and functional properties. Int Immunol 18:1375-84 (2006). PubMed: 16849394
- Guiducci C et al. Redirecting in vivo elicited tumor infiltrating macrophages and dendritic cells towards tumor rejection. Cancer Res 65:3437-46 (2005). PubMed: 15833879
- Esche C et al. CD154 inhibits tumor-induced apoptosis in dendritic cells and tumor growth. Eur J Immunol 29:2148-55 (1999). PubMed: 10427977
- Metlay JP et al. The distinct leukocyte integrins of mouse spleen dendritic cells as identified with new hamster monoclonal antibodies. J Exp Med 171:1753-71 (1990). PubMed: 2185332
- Bedford PG & Longstaffe JA Corneal pannus (chronic superficial keratitis) in the German shepherd dog. J Small Anim Pract 20:41-56 (1979). PubMed: 759720
- Cole DF Secretion of the aqueous humour. Exp Eye Res 25 Suppl:161-76 (1977). PubMed: 145370
