生物素Anti-Carboxymethyl Lysine抗体(ab27685)
Key features and details
- Biotin Goat polyclonal to Carboxymethyl Lysine
- Suitable for: WB, ELISA
- Reacts with: Species independent
- Conjugation: Biotin
- Isotype: IgG
概述
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产品名称
生物素Anti-Carboxymethyl Lysine抗体
参阅全部 Carboxymethyl Lysine 一抗 -
描述
生物素山羊多克隆抗体to Carboxymethyl Lysine -
宿主
Goat -
偶联物
Biotin -
经测试应用
适用于: WB, ELISAmore details -
种属反应性
与反应: Species independent -
免疫原
Carboxy methyl Lysine conjugated to KLH.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 6.5
Preservative: 0.02% Sodium azide
Constituents: 0.2% PBS, 0.0292% EDTA, 0.435% Sodium chloride, 30% Glycerol (glycerin, glycerine) -
Concentration information loading... -
纯度
Immunogen affinity purified -
纯化说明
This antibody was purified by Carboxy Methyl Lysine protein Sepharose affinity column. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab27685于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/2500 - 1/20000.
|
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| ELISA |
1/2500 - 1/20000.
|
| 说明 |
|---|
|
WB
1/2500 - 1/20000. |
|
ELISA
1/2500 - 1/20000. |
靶标
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相关性
N epsilon carboxymethyl lysine (CML or Carboxymethyl Lysine) is formed by the non enzymatic Schiff base reaction of glucose with proteins, followed by an Amadori rearrangement and oxidation that leaves only a carboxymethyl group attached to the lysine. The levels of CML adducts accumulate over time and have been used as an indicator of both serum glucose levels and oxidative protein damage. Elevated serum CML modified proteins have been associated with diabetes and may contribute to diabetic retinopathy, nephropathy and angiopathy. -
别名
- CML antibody
- N Epsilon (Carboxymethyl) Lysine antibody
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab27685 被引用在 1 文献中.
- Menini S et al. The advanced glycation end-product N? -carboxymethyllysine promotes progression of pancreatic cancer: implications for diabetes-associated risk and its prevention. J Pathol 245:197-208 (2018). PubMed: 29533466