生物素Anti-C5b-9 + C5b-8抗体[aE11] (ab237699)
Key features and details
- Biotin Mouse monoclonal [aE11] to C5b-9 + C5b-8
- Suitable for: ELISA
- Reacts with: Horse, Human, Pig, Baboon
- Conjugation: Biotin
- Isotype: IgG2a
Related conjugates and formulations
概述
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产品名称
生物素Anti-C5b-9 + C5b-8抗体[aE11] -
描述
生物素小鼠单克隆抗体[aE11] to C5b-9 + C5b-8 -
宿主
Mouse -
偶联物
Biotin -
特异性
ab237699 binds both membrane-bound MAC (active) and fluid-phase SC5b-9 complexes (inactive).
The aE11 monoclonal was first reported to bind to a neoepitope exposed on polymerized C9 when incorporated into the human terminal complement complex (PubMed ID: 4035298). It was subsequently shown that this antibody also cross reacts with the C5b-8 complex and purified C8 alpha-gamma. It does not react with native C9 or C8 proteins (PubMed ID: 2424021).
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经测试应用
适用于: ELISAmore details -
种属反应性
与反应: Horse, Human, Pig, Baboon -
免疫原
Full length native protein (purified) corresponding to Human C5b-9.
Database link: P01031 -
表位
ab237699 binds to a neoepitope exposed on C9. -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.40
Preservative: 0.0975% Sodium azide
Constituents: 0.16% Sodium phosphate, 0.81% Sodium chloride -
Concentration information loading...
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纯度
Affinity purified -
纯化说明
Biotinylated -
克隆
单克隆 -
克隆编号
aE11 -
同种型
IgG2a -
轻链类型
kappa -
研究领域
相关产品
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Alternative Versions
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab237699于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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ELISA |
Use at an assay dependent concentration.
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说明 |
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ELISA
Use at an assay dependent concentration. |
靶标
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细胞定位
C5b-9: Secreted -
数据库链接
- Entrez Gene: 727 Human
- Entrez Gene: 729 Human
- Entrez Gene: 730 Human
- Entrez Gene: 731 Human
- Entrez Gene: 735 Human
- SwissProt: P01031 Human
- SwissProt: P02748 Human
- SwissProt: P07357 Human
see all
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab237699 尚未被引用在任何文献中。