Anti-BFL-1/GRS抗体(ab45414)
Key features and details
- Rabbit polyclonal to BFL-1/GRS
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术，可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-BFL-1/GRS抗体
参阅全部 BFL-1/GRS 一抗 -
描述
兔多克隆抗体to BFL-1/GRS -
宿主
Rabbit -
特异性
At least two isoforms of Bcl2A1/GRS are known to exist; this antibody will detect both isoforms.
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经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide corresponding to Human BFL-1/GRS (N terminal). A 14 amino acid peptide from near the amino terminus of human BFL-1/GRS
Database link: Q16548 -
阳性对照
- WB: Human kidney tissue lysate.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at +4°C. -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab45414于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 39 kDa (predicted molecular weight: 20 kDa).
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| 说明 |
|---|
|
WB
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 39 kDa (predicted molecular weight: 20 kDa). |
靶标
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功能
Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection. -
组织特异性
Seems to be restricted to the hematopoietic compartment. Expressed in peripheral blood, spleen, and bone marrow, at moderate levels in lung, small intestine and testis, at a minimal levels in other tissues. Also found in vascular smooth muscle cells and hematopoietic malignancies. -
序列相似性
Belongs to the Bcl-2 family. -
细胞定位
Cytoplasm. - Information by UniProt
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数据库链接
- Entrez Gene: 597 Human
- Omim: 601056 Human
- SwissProt: Q16548 Human
- Unigene: 227817 Human
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别名
- ACC 1 antibody
- ACC 2 antibody
- B2LA1_HUMAN antibody
see all
图片
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Western blot - Anti-BFL-1/GRS antibody (ab45414)Lane 1 : Anti-BFL-1/GRS antibody (ab45414) at 1 µg/ml
Lane 2 : Anti-BFL-1/GRS antibody (ab45414) at 2 µg/ml
All lanes : Human kidney tissue lysate
Predicted band size: 20 kDa
Observed band size: 20 kDa
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab45414 被引用在 2 文献中.
- Liu F et al. UBQLN4 is an ATM substrate that stabilizes the anti-apoptotic proteins BCL2A1 and BCL2L10 in mesothelioma. Mol Oncol 15:3738-3752 (2021). PubMed: 34245648
- Gröschel M et al. Acute Noise Exposure Is Associated With Intrinsic Apoptosis in Murine Central Auditory Pathway. Front Neurosci 12:312 (2018). PubMed: 29867323