Anti-Betatrophin抗体- N-terminal (ab180915)
Key features and details
- Rabbit polyclonal to Betatrophin - N-terminal
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
概述
-
产品名称
Anti-Betatrophin抗体- N-terminal
参阅全部 Betatrophin 一抗 -
描述
兔多克隆抗体to Betatrophin - N-terminal -
宿主
Rabbit -
特异性
At least three isoforms of Betatrophin are known to exist (NP_061157, AAF76204 / EAW84186, EAW84185). ab180915 will detect the two largest isoforms of Betatrophin.
-
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Mouse, Rat, Human -
免疫原
Synthetic peptide corresponding to Human Betatrophin (N terminal). 16 amino acids long. NP_061157
Database link: Q6UXH0 -
阳性对照
- Rat liver tissue lysate.
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab180915于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 22 kDa (predicted molecular weight: 22 kDa).
|
|
| IHC-P |
Use a concentration of 5 µg/ml.
|
| 说明 |
|---|
|
WB
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 22 kDa (predicted molecular weight: 22 kDa). |
|
IHC-P
Use a concentration of 5 µg/ml. |
靶标
-
细胞定位
Secreted. - Information by UniProt
-
数据库链接
- Entrez Gene: 55908 Human
- SwissProt: Q6UXH0 Human
- Unigene: 534467 Human
-
别名
- Angiopoietin-like protein 8 antibody
- ANGPTL8 antibody
- betatrophin antibody
see all
图片
-
Western blot - Anti-Betatrophin antibody - N-terminal (ab180915)Lane 1 : Anti-Betatrophin antibody - N-terminal (ab180915) at 1 µg/ml
Lane 2 : Anti-Betatrophin antibody - N-terminal (ab180915) at 2 µg/ml
All lanes : Rat liver tissue lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 22 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Betatrophin antibody - N-terminal (ab180915)Immunofluorescence of Betatrophin in rat liver tissue with ab180915 at 20 μg/mL.
-
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Betatrophin antibody - N-terminal (ab180915)Immunohistochemistry of Betatrophin in rat liver tissue with ab180915 at 5 μg/mL.
数据表及文件
-
SDS download
-
Datasheet download
文献 (4)
ab180915 被引用在 4 文献中.
- Gao Y et al. Dual role of ANGPTL8 in promoting tumor cell proliferation and immune escape during hepatocarcinogenesis. Oncogenesis 12:26 (2023). PubMed: 37188659
- Li DP et al. LILRB2/PirB mediates macrophage recruitment in fibrogenesis of nonalcoholic steatohepatitis. Nat Commun 14:4436 (2023). PubMed: 37481670
- Zhang D et al. Recombinant betatrophin (Angptl-8/lipasin) ameliorates streptozotocin-induced hyperglycemia and ß-cell destruction in neonatal rats. Mol Med Rep 20:4523-4532 (2019). PubMed: 31702044
- Wang R et al. Neuropeptide Y-Positive Neurons in the Dorsomedial Hypothalamus Are Involved in the Anorexic Effect of Angptl8. Front Mol Neurosci 11:451 (2018). PubMed: 30618603