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AB10505

Anti-BDNF抗体[35928.11]

Anti-BDNF antibody [35928.11]

4

(1 Review)

|

(14 Publications)

Mouse Monoclonal BDNF antibody. Suitable for ELISA, WB, IHC-P and reacts with Human samples. Cited in 14 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human BDNF.

查看别名

Neurotrophic factor BDNF precursor form, proBDNF, Abrineurin, Brain-derived neurotrophic factor, BDNF

关键信息

宿主种属

Mouse

克隆

Monoclonal

克隆号

35928.11

亚型

IgG1

不含载体蛋白

No

反应种属

Human

应用

IHC-P, ELISA, WB

applications

免疫原

Recombinant Full Length Protein corresponding to Human BDNF.

P23560

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>" } } }
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您是否考虑以下替代产品？

AB213323

Anti-BDNF antibody [EPR21211]

0
0 Reviews
查看产品
为什么推荐这个？

为向您提供最高品质的产品，我们在不断升级产品范围。我们选择了这个替代产品供您参考，因为它提供了更好的性能，更容易和更方便的使用，或交期更快。

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产品详情

Endotoxin: <10 ng/mg by LAL method. For BDNF, multiple WB bands are possible and expected. The human protein has 5 isoforms (precursors: 28 – 37 kDa) and can be glycosylated (Uniprot: http://www.uniprot.org/uniprot/P23560). The mature form is expected at ~14 kDa (monomer) and the dimer at ~28 kDa.
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性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Protein A
纯化说明
The antibody is purified by Protein A affinity chromatography.
存储溶液
Constituents: PBS
运输条件
Blue Ice
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle
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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:
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靶点信息

The protein expressed by the BDNF gene is a critical signaling molecule that activates pathways downstream of NTRK2, as well as the heterodimeric receptor formed by NGFR and SORCS2. During development, it aids the survival and differentiation of specific neuronal populations in both the peripheral and central nervous systems. It is involved in axonal growth, pathfinding, and modulation of dendritic growth and morphology. In adult synapses, BDNF is a key regulator of synaptic transmission and plasticity in various CNS regions, contributing to processes like long-term potentiation, long-term depression, some short-term synaptic plasticity forms, and the homeostatic regulation of intrinsic neuronal excitability. Signaling through NGFR and SORCS2 is linked to synaptic plasticity and long-term depression, while its binding to these receptors also promotes neuronal apoptosis. This supplementary information is collated from multiple sources and compiled automatically.
See full target information BDNF
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文献 (14)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in cellular neuroscience 16:812887 PubMed35418836

2022

Metabolic Reprogramming in HIV-Associated Neurocognitive Disorders.

Applications

Unspecified application

Species

Unspecified reactive species

Charles N S Allen,Sterling P Arjona,Maryline Santerre,Claudio De Lucia,Walter J Koch,Bassel E Sawaya

Frontiers in medicine 7:353 PubMed32793611

2020

LncRNA Rik-203 Contributes to Sevoflurane Induced Neurotoxicity?

Applications

Unspecified application

Species

Unspecified reactive species

Lei Zhang,Zhenyu Xue,Jia Yan,Hong Jiang

Aging 12:11446-11465 PubMed32544883

2020

microRNA-9 and -29a regulate the progression of diabetic peripheral neuropathy ISL1-mediated sonic hedgehog signaling pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Qin Sun,Jun Zeng,Yang Liu,JingYan Chen,Qing-Cui Zeng,Yan-Qiu Chen,Li-Li Tu,Ping Chen,Fan Yang,Min Zhang

Journal of oral rehabilitation 47:843-850 PubMed32277715

2020

Daytime changes of salivary biomarkers involved in pain.

Applications

Unspecified application

Species

Unspecified reactive species

Hajer Jasim,Bijar Ghafouri,Anders Carlsson,Britt Hedenberg-Magnusson,Malin Ernberg

Brain and behavior 8:e01127 PubMed30298999

2018

Total saponins from the leaves of Panax notoginseng inhibit depression on mouse chronic unpredictable mild stress model by regulating circRNA expression.

Applications

Unspecified application

Species

Unspecified reactive species

Hualin Zhang,Ziming Chen,Zhiyong Zhong,Weifan Gong,Jun Li

The American journal of pathology 188:2281-2292 PubMed30031725

2018

IL-1β Stimulates Brain-Derived Neurotrophic Factor Production in Eutopic Endometriosis Stromal Cell Cultures: A Model for Cytokine Regulation of Neuroangiogenesis.

Applications

Unspecified application

Species

Unspecified reactive species

Jie Yu,Antônio M C Francisco,Bansari G Patel,J Mark Cline,Eric Zou,Sarah L Berga,Robert N Taylor

Scientific reports 8:3220 PubMed29459715

2018

Saliva as a medium to detect and measure biomarkers related to pain.

Applications

Unspecified application

Species

Unspecified reactive species

Hajer Jasim,Anders Carlsson,Britt Hedenberg-Magnusson,Bijar Ghafouri,Malin Ernberg

Molecular medicine reports 17:4083-4089 PubMed29257320

2017

MicroRNA-103 suppresses glioma cell proliferation and invasion by targeting the brain-derived neurotrophic factor.

Applications

Unspecified application

Species

Unspecified reactive species

Ling Wang,Ying Liu,Jianwei Song

Scientific reports 6:28599 PubMed27345430

2016

Focused ultrasound-enhanced intranasal brain delivery of brain-derived neurotrophic factor.

Applications

Unspecified application

Species

Unspecified reactive species

Hong Chen,Georgiana Zong Xin Yang,Hoheteberhan Getachew,Camilo Acosta,Carlos Sierra Sánchez,Elisa E Konofagou

Molecular medicine reports 13:441-6 PubMed26549320

2015

MicroRNA‑10b suppresses the migration and invasion of chondrosarcoma cells by targeting brain‑derived neurotrophic factor.

Applications

Unspecified application

Species

Unspecified reactive species

Abudunaibi Aili,Yong Chen,Hongqi Zhang
View all publications
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Abcam Product Promise

我们致力于为您的研究提供高质量的试剂，为您科研的每一步提供支持。若我们的产品未能达到预期性能，我们向您提供 Abcam Product Promise 保障。
详情请参阅我们的条款与条件。
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