Anti-BANP抗体(ab72076)
Key features and details
- Rabbit polyclonal to BANP
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Human
- Isotype: IgG
概述
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产品名称
Anti-BANP抗体 -
描述
兔多克隆抗体to BANP -
宿主
Rabbit -
经测试应用
适用于: IHC-P, WBmore details -
种属反应性
与反应: Mouse, Human
预测可用于: Rabbit, Horse, Guinea pig, Cow, Dog, Chimpanzee, Rhesus monkey, Chinese hamster, Orangutan
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免疫原
Synthetic peptide corresponding to a region between residue 425 and the C-terminus (residue 469) of human BANP (TrEMBL entry Q96GJ7)
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7
Preservative: 0.09% Sodium azide
Constituents: 1.815% Tris, 1.764% Sodium citrate, 0.021% PBS -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab72076于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P |
1/2000 - 1/10000.
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| WB |
1/10000 - 1/25000. Predicted molecular weight: 59 kDa.
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| 说明 |
|---|
|
IHC-P
1/2000 - 1/10000. |
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WB
1/10000 - 1/25000. Predicted molecular weight: 59 kDa. |
靶标
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功能
Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest. -
组织特异性
Down-regulated in breast cancer cell lines. -
序列相似性
Belongs to the BANP/SMAR1 family.
Contains 1 BEN domain. -
细胞定位
Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 54971 Human
- Entrez Gene: 53325 Mouse
- Omim: 611564 Human
- SwissProt: Q8N9N5 Human
- SwissProt: Q8VBU8 Mouse
- Unigene: 461705 Human
- Unigene: 287163 Mouse
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别名
- AAH09424 antibody
- Banp antibody
- BANP_HUMAN antibody
see all
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BANP antibody (ab72076)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of mouse renal cell tissue labelling BANP with ab72076 at 1/5000 (0.2µg/ml). Setection: DAB.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BANP antibody (ab72076)Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human lung carcinoma tissue labelling BANP with ab72076 at 1/5000 (0.2µg/ml). Setection: DAB.
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Western blot - Anti-BANP antibody (ab72076)All lanes : Anti-BANP antibody (ab72076) at 0.1 µg/ml
Lane 1 : HeLa whole cell lysate
Lane 2 : HEK293T whole cell lysate
Lane 3 : NIH 3T3 whole cell lysate
Lysates/proteins at 50 µg per lane.
Predicted band size: 59 kDa
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab72076 尚未被引用在任何文献中。