Anti-Bacillus anthracis protective antigen抗体(ab13808)
Key features and details
- Rabbit polyclonal to Bacillus anthracis protective antigen
- Suitable for: WB
- Reacts with: Bacillus anthracis
- Isotype: IgG
概述
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产品名称
Anti-Bacillus anthracis protective antigen抗体
参阅全部 Bacillus anthracis protective antigen 一抗 -
描述
兔多克隆抗体to Bacillus anthracis protective antigen -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Bacillus anthracis -
免疫原
Synthetic peptide corresponding to amino acids 238-254 of Anthrax PA
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
Preservative: 0.05% Sodium azide
Constituents: PBS, 0.05% BSA -
Concentration information loading... -
纯度
Whole antiserum -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab13808于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/1000. Detects a band of approximately 83 kDa.
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| 说明 |
|---|
|
WB
1/1000. Detects a band of approximately 83 kDa. |
靶标
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相关性
Anthrax toxins are composed of three distinct proteins, a protective antigen (PA), a lethal factor (LF) and an edema factor (EF). None of these proteins are toxic by themselves and several studies indicate that the anthrax toxin has the familiar A-B enzymatic binding structure, with PA acting as the binding domain and EF and/or LF acting as the active fragments. -
细胞定位
Secreted -
别名
- PA antibody
- PA83 antibody
- pag antibody
see all
图片
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Western blot - Anti-Bacillus anthracis protective antigen antibody (ab13808)
Western blot analysis of Anthrax PA in recombinant protein using ab13808 (lane B) at 1:1000 dilution. Lane A shows the pre-bleed.
数据表及文件
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SDS download
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Datasheet download
文献 (6)
ab13808 被引用在 6 文献中.
- Hu J et al. Increased Excess Intracellular Cyclic di-AMP Levels Impair Growth and Virulence of Bacillus anthracis. J Bacteriol 202:N/A (2020). PubMed: 32071095
- Larkin IN et al. Dual-Readout Sandwich Immunoassay for Device-Free and Highly Sensitive Anthrax Biomarker Detection. Anal Chem 92:7845-7851 (2020). PubMed: 32437125
- Dyer PDR et al. Disarmed anthrax toxin delivers antisense oligonucleotides and siRNA with high efficiency and low toxicity. J Control Release 220:316-328 (2015). PubMed: 26546271
- Kim SK et al. Comparative analysis of virulence factors secreted by Bacillus anthracis Sterne at host body temperature. Lett Appl Microbiol 54:306-12 (2012). PubMed: 22268495
- Wilson MK et al. Bacillus cereus G9241 makes anthrax toxin and capsule like highly virulent B. anthracis Ames but behaves like attenuated toxigenic nonencapsulated B. anthracis Sterne in rabbits and mice. Infect Immun 79:3012-9 (2011). WB . PubMed: 21576337
- Martchenko M et al. Heterodimeric integrin complexes containing beta1-integrin promote internalization and lethality of anthrax toxin. Proc Natl Acad Sci U S A 107:15583-8 (2010). WB . PubMed: 20713715