Anti-ATPAF2抗体(ab74235)
Key features and details
- Rabbit polyclonal to ATPAF2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-ATPAF2抗体 -
描述
兔多克隆抗体to ATPAF2 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Mouse
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免疫原
A synthesized peptide derived from the internal region of human ATPAF2.
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阳性对照
- Extracts from Jurkat cells.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, PBS -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab74235于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/500 - 1/1000. Detects a band of approximately 33 kDa (predicted molecular weight: 33 kDa).
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| 说明 |
|---|
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WB
1/500 - 1/1000. Detects a band of approximately 33 kDa (predicted molecular weight: 33 kDa). |
靶标
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相关性
ATPAF2 belongs to the ATP12 family. It may play a role in the assembly of the F1 component of the mitochondrial ATP synthase (ATPase). Defects in ATPAF2 are the cause of complex V mitochondrial respiratory chain ATPAF2 subunit deficiency (ATPAF2 deficiency) [MIM:604273]; also called ATP synthase deficiency or ATPase deficiency. ATPAF2 deficiency seems to be an early presenting disease in which lactic acidosis, dysmorphic features, and methyl glutaconic aciduria can be major clues in the diagnosis. Dysmorphic features include a large mouth, prominent nasal bridge, micrognathia, rocker-bottom feet and flexion contractures of the limbs associated with camptodactyly. Patients are hypertonic and have an enlarged liver, hypoplastic kidneys and elevated lactate levels in urine, plasma and cerebro spinal fluid (CSF). -
细胞定位
Mitochondrion -
数据库链接
- Entrez Gene: 91647 Human
- Entrez Gene: 246782 Mouse
- Omim: 608918 Human
- SwissProt: Q8N5M1 Human
- SwissProt: Q91YY4 Mouse
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别名
- ATP synthase mitochondrial F1 complex assembly factor 2 antibody
- ATP12 antibody
- ATP12 homolog antibody
see all
图片
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Western blot - Anti-ATPAF2 antibody (ab74235)All lanes : Anti-ATPAF2 antibody (ab74235) at 1/500 dilution
Lane 1 : Extracts from Jurkat cells
Lane 2 : Extracts from Jurkat cells plus 5µg immunizing peptide
Lysates/proteins at 5 µg per lane.
Predicted band size: 33 kDa
Observed band size: 33 kDa
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab74235 尚未被引用在任何文献中。