Anti-ATF-4 (phospho S245)抗体(ab28830)
Key features and details
- Rabbit polyclonal to ATF-4 (phospho S245)
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-ATF-4 (phospho S245)抗体
参阅全部 ATF-4 一抗 -
描述
兔多克隆抗体to ATF-4 (phospho S245) -
宿主
Rabbit -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide corresponding to Human ATF-4 (phospho S245).
Database link: P18848 -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Corresponding non-phospho antibody
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab28830于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P |
1/50 - 1/100.
|
| 说明 |
|---|
|
IHC-P
1/50 - 1/100. |
靶标
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功能
Transcriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. It binds to a Tax-responsive enhancer element in the long terminal repeat of HTLV-I. -
序列相似性
Belongs to the bZIP family.
Contains 1 bZIP domain. -
细胞定位
Cytoplasm. Cell membrane. Nucleus. Colocalizes with GABBR1 in hippocampal neuron dendritic membranes. - Information by UniProt
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数据库链接
- Entrez Gene: 468 Human
- Omim: 604064 Human
- SwissProt: P18848 Human
- Unigene: 496487 Human
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别名
- Activating transcription factor 4 antibody
- ATF 4 antibody
- ATF4 antibody
see all
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ATF-4 (phospho S245) antibody (ab28830)Immunohistochemistry (Formalin-fixed paraffin-embedded sections) staining of breast carcinoma using ab28830
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ATF-4 (phospho S245) antibody (ab28830)Immunohistochemistry (Formalin-fixed paraffin-embedded sections) staining of breast carcinoma using ab28830 treated with synthesised phospho-peptide.
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (6)
ab28830 被引用在 6 文献中.
- Comandante-Lou N et al. AP-1 transcription factor network explains diverse patterns of cellular plasticity in melanoma cells. Cell Rep 40:111147 (2022). PubMed: 35926467
- Selimovic D et al. Tumor necrosis factor-a triggers opposing signals in head and neck squamous cell carcinoma and induces apoptosis via mitochondrial- and non-mitochondrial-dependent pathways. Int J Oncol 55:1324-1338 (2019). PubMed: 31638203
- González-González A et al. Activating Transcription Factor 4 Modulates TGFß-Induced Aggressiveness in Triple-Negative Breast Cancer via SMAD2/3/4 and mTORC2 Signaling. Clin Cancer Res 24:5697-5709 (2018). PubMed: 30012564
- El-Khattouti A et al. Imiquimod-induced apoptosis of melanoma cells is mediated by ER stress-dependent Noxa induction and enhanced by NF-?B inhibition. J Cell Mol Med 20:266-86 (2016). WB . PubMed: 26578344
- Kalamida D et al. Important role of autophagy in endothelial cell response to ionizing radiation. PLoS One 9:e102408 (2014). WB ; Human . PubMed: 25010689
- Myers SA et al. CD36 deletion improves recovery from spinal cord injury. Exp Neurol 256:25-38 (2014). PubMed: 24690303