重组Anti-ARIH2/TRIAD1抗体[EPR7671] (ab133653)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR7671] to ARIH2/TRIAD1
- Suitable for: WB
- Reacts with: Rat, Human
Related conjugates and formulations
概述
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产品名称
Anti-ARIH2/TRIAD1抗体[EPR7671]
参阅全部 ARIH2/TRIAD1 一抗 -
描述
兔单克隆抗体[EPR7671] to ARIH2/TRIAD1 -
宿主
Rabbit -
经测试应用
适用于: WBmore details
不适用于: Flow Cyt or IHC-P -
种属反应性
与反应: Rat, Human
预测可用于: Mouse -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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阳性对照
- 293T, Jurkat, HeLa and PC12 cell lysates
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常规说明
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
解离常数(KD)
KD = 9.00 x 10 -12 M Learn more about KD -
存储溶液
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading...
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纯度
Protein A purified -
克隆
单克隆 -
克隆编号
EPR7671 -
同种型
IgG -
研究领域
相关产品
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Alternative Versions
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab133653于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/1000 - 1/10000. Predicted molecular weight: 57 kDa.
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说明 |
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WB
1/1000 - 1/10000. Predicted molecular weight: 57 kDa. |
靶标
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功能
E3 ubiquitin-protein ligase mediating 'Lys-48'-and 'Lys-63'-linked polyubiquitination and subsequent proteasomal degradation of modified proteins. May play a role in myelopoiesis. -
组织特异性
Widely expressed with higher expression in granulocytes. -
通路
Protein modification; protein ubiquitination. -
序列相似性
Belongs to the RBR family. Ariadne subfamily.
Contains 1 IBR-type zinc finger.
Contains 2 RING-type zinc fingers. -
结构域
RING-type 1 and RING-type 2 are required for the inhibitory function in myelopoiesis. -
翻译后修饰
Ubiquitinated. Ubiquitination promotes proteasomal degradation.
Phosphorylated upon DNA damage, probably by ATM or ATR. -
细胞定位
Nucleus. Cytoplasm. - Information by UniProt
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数据库链接
- Entrez Gene: 10425 Human
- Entrez Gene: 23807 Mouse
- Entrez Gene: 316005 Rat
- Omim: 605615 Human
- SwissProt: O95376 Human
- SwissProt: Q9Z1K6 Mouse
- Unigene: 633601 Human
- Unigene: 290447 Mouse
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别名
- HT005 antibody
- all trans retinoic acid inducible RING finger antibody
- Ari 2 antibody
see all
图片
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All lanes : Anti-ARIH2/TRIAD1 antibody [EPR7671] (ab133653) at 1/1000 dilution
Lane 1 : 293T cell lysate
Lane 2 : Jurkat cell lysate
Lane 3 : HeLa cell lysate
Lane 4 : PC12 cell lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : Goat anti-Rabbit HRP at 1/2000 dilution
Predicted band size: 57 kDa
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab133653 尚未被引用在任何文献中。