Anti-ARF1抗体(ab76082)
Key features and details
- Rabbit polyclonal to ARF1
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
概述
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产品名称
Anti-ARF1抗体
参阅全部 ARF1 一抗 -
描述
兔多克隆抗体to ARF1 -
宿主
Rabbit -
特异性
ab76082 does not cross react to other members of the Ras family or to other ARF members. This antibody will label ARF 1 isoform 1, 2, 3 and 4. -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Mouse, Rat, Human -
免疫原
Synthetic peptide corresponding to a unique epitope on Rat ARF1 protein. The peptide was covalently modified post-synthetically to achieve desired antigenicity.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab76082于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/500. Predicted molecular weight: 21 kDa.
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| 说明 |
|---|
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WB
1/500. Predicted molecular weight: 21 kDa. |
靶标
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功能
GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking among different compartments. Modulates vesicle budding and uncoating within the Golgi complex. Deactivation induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, suggesting a crucial role in protein trafficking. In its GTP-bound form, its triggers the association with coat proteins with the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles. -
序列相似性
Belongs to the small GTPase superfamily. Arf family. -
细胞定位
Golgi apparatus. Cytoplasm > perinuclear region. - Information by UniProt
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数据库链接
- Entrez Gene: 375 Human
- Entrez Gene: 11840 Mouse
- Entrez Gene: 64310 Rat
- Omim: 103180 Human
- SwissProt: P84077 Human
- SwissProt: P84078 Mouse
- SwissProt: P84079 Rat
- Unigene: 286221 Human
see all -
别名
- ADP Ribosylation Factor 1 antibody
- ADP-ribosylation factor 1 antibody
- ARF 1 antibody
see all
图片
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Western blot - Anti-ARF1 antibody (ab76082)Anti-ARF1 antibody (ab76082) at 1/500 dilution + Rat cerebal cortex
Predicted band size: 21 kDa
数据表及文件
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Datasheet download
文献 (0)
ab76082 尚未被引用在任何文献中。
