Anti-Aquaporin 5抗体(ab78486)
Key features and details
- Rabbit polyclonal to Aquaporin 5
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Rat
- Isotype: IgG
概述
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产品名称
Anti-Aquaporin 5抗体
参阅全部 Aquaporin 5 一抗 -
描述
兔多克隆抗体to Aquaporin 5 -
宿主
Rabbit -
经测试应用
适用于: IHC-P, WBmore details -
种属反应性
与反应: Mouse, Rat -
免疫原
A 17 amino acid synthetic peptide corresponding to the carboxy terminus of rat Aquaporin 5
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
Preservative: 0.05% Sodium azide
Constituent: PBS -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab78486于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P | (1) |
Use a concentration of 2 - 10 µg/ml.
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| WB | (1) |
Use a concentration of 0.05 - 0.1 µg/ml. Predicted molecular weight: 24 kDa.
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| 说明 |
|---|
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IHC-P
Use a concentration of 2 - 10 µg/ml. |
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WB
Use a concentration of 0.05 - 0.1 µg/ml. Predicted molecular weight: 24 kDa. |
靶标
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功能
Forms a water-specific channel. Implicated in the generation of saliva, tears, and pulmonary secretions. Required for TRPV4 activation by hypotonicity (PubMed:16571723). Together with TRPV4, controls regulatory volume decrease in salivary epithelial cells (PubMed:16571723). -
疾病相关
Keratoderma, palmoplantar, Bothnian type -
序列相似性
Belongs to the MIP/aquaporin (TC 1.A.8) family. -
结构域
Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA). -
细胞定位
Apical cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 11830 Mouse
- Entrez Gene: 25241 Rat
- SwissProt: Q9WTY4 Mouse
- SwissProt: P47864 Rat
- Unigene: 45580 Mouse
- Unigene: 10066 Rat
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别名
- AQP 5 antibody
- AQP-5 antibody
- AQP5 antibody
see all
图片
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Western blot - Anti-Aquaporin 5 antibody (ab78486)Anti-Aquaporin 5 antibody (ab78486) at 0.1 µg/ml + Rat salivary gland tissue lysate
Secondary
Goat Anti-Rabbit IgG secondary antibody conjugated to HRP
Predicted band size: 24 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Aquaporin 5 antibody (ab78486)Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) staining Aquaporin 5 with ab78486 (1/2000) in rat lung. An anti-Rabbit secondary antibody and HRP-DAB was used. Tissues were processed using heat-induced epitope retrieval.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Aquaporin 5 antibody (ab78486)Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) staining Aquaporin 5 with ab78486 (1/500) in mouse trachea tissue. An anti-Rabbit secondary antibody and HRP-DAB was used. Tissues were processed using heat-induced epitope retrieval.
数据表及文件
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SDS download
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Datasheet download
文献 (70)
ab78486 被引用在 70 文献中.
- Liu J et al. Oxidative-antioxidant imbalance in chronic sialadenitis of submandibular gland in human and rat. Oral Dis 29:1005-1016 (2023). PubMed: 34826194
- Wang B et al. Sialin mediates submandibular gland regeneration ability by affecting polysialic acid synthesis. Oral Dis 29:2096-2106 (2023). PubMed: 35593110
- He H et al. Activating NO-sGC crosstalk in the mouse vascular niche promotes vascular integrity and mitigates acute lung injury. J Exp Med 220:N/A (2023). PubMed: 36350314
- Wang X et al. Soy isoflavone reduces LPS-induced acute lung injury via increasing aquaporin 1 and aquaporin 5 in rats. Open Life Sci 18:20220560 (2023). PubMed: 36820212
- Ismail NH et al. Modulation of vulvovaginal atrophy (VVA) by Gelam honey in bilateral oophorectomized rats. Front Endocrinol (Lausanne) 14:1031066 (2023). PubMed: 36923220