Anti-Apoptosis enhancing nuclease抗体(ab97915)
Key features and details
- Rabbit polyclonal to Apoptosis enhancing nuclease
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-Apoptosis enhancing nuclease抗体 -
描述
兔多克隆抗体to Apoptosis enhancing nuclease -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide, corresponding to a region within amino acids 236-297 of Apoptosis enhancing nuclease (NP_073604).
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阳性对照
- HeLa, HepG2 or MOLT4 cell lines.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab97915于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/500 - 1/3000. Predicted molecular weight: 36 kDa.
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| IHC-P |
1/100 - 1/250.
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| 说明 |
|---|
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WB
1/500 - 1/3000. Predicted molecular weight: 36 kDa. |
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IHC-P
1/100 - 1/250. |
靶标
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功能
Exonuclease with activity against single- and double-stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis. -
序列相似性
Contains 1 exonuclease domain. -
细胞定位
Nucleus. Nucleus > nucleolus. Localized predomintly in the nucleolus. Translocates from the nucleolus to the nucleoplasm upon apoptosis induction. - Information by UniProt
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数据库链接
- Entrez Gene: 64782 Human
- Omim: 610177 Human
- SwissProt: Q8WTP8 Human
- Unigene: 436102 Human
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别名
- Aen antibody
- AEN_HUMAN antibody
- apoptosis enhancing nuclease antibody
see all
图片
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Western blot - Anti-Apoptosis enhancing nuclease antibody (ab97915)Anti-Apoptosis enhancing nuclease antibody (ab97915) at 1/1000 dilution + HeLa whole cell lysate at 30 µg
Predicted band size: 36 kDa
10% SDS PAGE -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Apoptosis enhancing nuclease antibody (ab97915)ab97915, at 1/100 dilution, staining Apoptosis enhancing nuclease in Cal27 xenograft tissue by Immunohistochemistry. Formalin-fixed, paraffin-embedded section.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab97915 尚未被引用在任何文献中。