AB232710

Anti-Apolipoprotein CIV抗体

Name: Apolipoprotein CIV抗体 (ab232710)| Abcam中文官网
Brand: Abcam Limited
SKU: AB232710
Price: 4748 CNY
Availability: InStock

Anti-Apolipoprotein CIV antibody

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(2 Publications)

Rabbit Polyclonal Apolipoprotein CIV antibody. Suitable for WB, IHC-P and reacts with Mouse samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Mouse Apoc4 aa 1 to C-terminus.

查看别名

Acl, Apoc4, Apolipoprotein C-IV, Apo-CIV, ApoC-IV, Apolipoprotein C2-linked, Apolipoprotein C4, ACL

4 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Apolipoprotein CIV antibody (AB232710)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Apolipoprotein CIV antibody (AB232710)

Formalin-fixed, paraffin-embedded mouse liver tissue stained for Apolipoprotein CIV using ab232710 at 20 μg/ml in immunohistochemical analysis. DAB staining.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Apolipoprotein CIV antibody (AB232710)

Formalin-fixed, paraffin-embedded mouse kidney tissue stained for Apolipoprotein CIV using ab232710 at 20 μg/ml in immunohistochemical analysis. DAB staining.

Supplier Data

Western blot - Anti-Apolipoprotein CIV antibody (AB232710)

All lanes:

Western blot - Anti-Apolipoprotein CIV antibody (ab232710) at 1 µg/mL

All lanes:

Mouse serum

Secondary

All lanes:

HRP-Linked Guinea pig anti-rabbit at 1/2000 dilution

Predicted band size: 15 kDa

false

Supplier Data

Western blot - Anti-Apolipoprotein CIV antibody (AB232710)

All lanes:

Western blot - Anti-Apolipoprotein CIV antibody (ab232710) at 1 µg/mL

All lanes:

Recombinant mouse Apolipoprotein CIV protein

Secondary

All lanes:

HRP-Linked Guinea pig Anti-Rabbit Ab at 1/2000 dilution

Predicted band size: 15 kDa

false

关键信息

宿主种属

Rabbit

克隆

Polyclonal

亚型

IgG

不含载体蛋白

反应种属

Mouse

应用

IHC-P, WB

applications

免疫原

Recombinant Fragment Protein within Mouse Apoc4 aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q61268

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-2 µg/mL", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "5-20 µg/mL", "IHCP-species-notes": "<p></p>" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

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性能和储存信息

形式

Liquid

纯化工艺

Affinity purification Immunogen

纯化说明

Antigen-specific affinity chromatography followed by Protein A affinity chromatography.

存储溶液

pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 55.77% Glycerol (glycerin, glycerine)

运输条件

Blue Ice

分装信息

Upon delivery aliquot

储存信息

Avoid freeze / thaw cycle

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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

Apolipoprotein CIV (ApoC-IV) is a member of the apolipoprotein family. Structurally it weighs approximately 11 kDa and is expressed mainly in the liver. In terms of function it participates in lipid transport and metabolism acting as a component of lipoprotein particles. ApoC-IV modifies the activity of enzymes involved in lipid metabolism impacting lipid levels in the bloodstream.

Biological function summary

ApoC-IV plays a significant role in the regulation of triglyceride-rich lipoproteins. It is not part of a larger protein complex but interacts with various components within the lipoprotein transportation system. Its activity affects the breakdown and utilization of lipids influencing lipid homeostasis in the body. Studies suggest that ApoC-IV might have an impact on the efficiency of lipoprotein lipase which is essential for lipid metabolism.

Pathways

ApoC-IV functions in lipid metabolic processes notably within the triglyceride-rich lipoprotein metabolism pathway. It interacts with other apolipoproteins such as Apolipoprotein CIII (ApoC-III) and Apolipoprotein E (ApoE) which also contribute to lipid regulation in this pathway. These interactions help maintain balance in lipid levels and ensure proper lipid distribution through tissues.

ApoC-IV links to cardiovascular disease and hyperlipidemia. It can influence plasma lipid levels and contribute to lipid imbalances associated with these conditions. ApoC-IV functions alongside proteins like ApoE and ApoB in these diseases where abnormal lipid transport and metabolism can exacerbate disease progression. Understanding its role offers insights into potential therapeutic targets for lipid-related disorders.

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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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靶点信息

May participate in lipoprotein metabolism.

See full target information Apoc4

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文献 (2)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in microbiology 15:1452739 PubMed39749135

2025

Limitations of a proper SFTSV mouse model using human C-type lectin receptors.

Applications

Unspecified application

Species

Unspecified reactive species

You-Min Kim,Hyo-Jin Ro,Jae Hoon Lee,Yaechan Song,Han-Woong Lee,Nam-Hyuk Cho

Proteomics 22:e2100028 PubMed35234362

2022

Effects of ABCG1 knockout on proteomic composition of HDL in mice on a chow diet and a high-fat diet.

Applications

Unspecified application

Species

Unspecified reactive species

Yanxiang Wu,Lianfeng Chen,Ziyan Xie,Chenyu Wang,Jiahao Zhang,Xiaowei Yan

View all publications

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Anti-Apolipoprotein CIV抗体

Anti-Apolipoprotein CIV antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Apolipoprotein CIV antibody (AB232710)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Apolipoprotein CIV antibody (AB232710)

Western blot - Anti-Apolipoprotein CIV antibody (AB232710)

Western blot - Anti-Apolipoprotein CIV antibody (AB232710)