Anti-APOBEC1抗体(ab80493)
Key features and details
- Goat polyclonal to APOBEC1
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
概述
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产品名称
Anti-APOBEC1抗体 -
描述
山羊多克隆抗体to APOBEC1 -
宿主
Goat -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Mouse
预测可用于: Human, Orangutan
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免疫原
Synthetic peptide:
DVFYDPRELRKEAC
, corresponding to internal sequence amino acids 24-37 of Human APOBEC1 (NP_001635.2). -
阳性对照
- Mouse spleen lysate.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% BSA, 0.5% Tris buffered saline -
Concentration information loading... -
纯度
Immunogen affinity purified -
纯化说明
ab80493 is purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab80493于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
| 说明 |
|---|
应用说明
Peptide ELISA: antibody detection limit dilution 1/32000.
WB: Use at a concentration of 1 - 3 µg/ml. Detects a band of approximately 28 kDa (predicted molecular weight: 28 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
WB: Use at a concentration of 1 - 3 µg/ml. Detects a band of approximately 28 kDa (predicted molecular weight: 28 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
靶标
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功能
Catalytic component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the APOB mRNA. Also involved in CGA (Arg) to UGA (Stop) editing in the NF1 mRNA. -
组织特异性
Expressed exclusively in the small intestine. -
序列相似性
Belongs to the cytidine and deoxycytidylate deaminase family. - Information by UniProt
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数据库链接
- Entrez Gene: 339 Human
- Entrez Gene: 11810 Mouse
- GenBank: L25877 Human
- GenBank: U21951 Mouse
- Omim: 600130 Human
- SwissProt: P41238 Human
- SwissProt: P51908 Mouse
- SwissProt: Q694B3 Orangutan
see all -
别名
- ABEC1_HUMAN antibody
- APOBEC 1 antibody
- APOBEC1 antibody
see all
图片
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Western blot - Anti-APOBEC1 antibody (ab80493)Anti-APOBEC1 antibody (ab80493) at 1 µg/ml + mouse spleen lysate (in RIPA buffer) at 35 µg
Predicted band size: 28 kDa
Observed band size: 28 kDa
Primary incubation was 1 hour.
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab80493 被引用在 1 文献中.
- Fossat N et al. C to U RNA editing mediated by APOBEC1 requires RNA-binding protein RBM47. EMBO Rep : (2014). PubMed: 24916387