重组APC Anti-Sialoadhesin/CD169抗体[EPR27102-11] (ab317480)
![Flow Cytometry - APC Anti-Sialoadhesin/CD169 antibody [EPR27102-11] (ab317480)](https://www.abcam.cn/ps/products/317/ab317480/Images/ab317480-1-apc-anti-sialoadhesincd169-antibody-epr27102-11-flow-cytometry-mouse-bone-marrow-cells.jpg "Flow Cytometry - APC Anti-Sialoadhesin/CD169 antibody [EPR27102-11] (ab317480)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- APC Rabbit monoclonal [EPR27102-11] to Sialoadhesin/CD169
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: APC. Ex: 645nm, Em: 660nm
Related conjugates and formulations
概述
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产品名称
APC Anti-Sialoadhesin/CD169抗体[EPR27102-11]
参阅全部 Sialoadhesin/CD169 一抗 -
描述
APC兔单克隆抗体[EPR27102-11] to Sialoadhesin/CD169 -
宿主
Rabbit -
偶联物
APC. Ex: 645nm, Em: 660nm -
经测试应用
适用于: Flow Cytmore details
不适用于: ICC/IF -
种属反应性
与反应: Mouse -
免疫原
Recombinant fragment. This information is proprietary to Abcam and/or its suppliers.
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阳性对照
- Flow Cyt: Mouse bone marrow cells.
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常规说明
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at +4°C. Avoid freeze / thaw cycle. Store In the Dark. -
存储溶液
pH: 7.4
Preservative: 0.02% Sodium azide
Constituents: 98% PBS, 1% BSA -
Concentration information loading... -
纯度
Protein A purified -
克隆
单克隆 -
克隆编号
EPR27102-11 -
同种型
IgG -
研究领域
相关产品
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Alternative Versions
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab317480于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| Flow Cyt |
1/5000.
|
| 说明 |
|---|
|
Flow Cyt
1/5000. |
靶标
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功能
Acts as an endocytic receptor mediating clathrin dependent endocytosis. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. Preferentially binds to alpha-2,3-linked sialic acid (By similarity). Binds to SPN/CD43 on T-cells (By similarity). May play a role in hemopoiesis. -
组织特异性
Expressed by macrophages in various tissues. High levels are found in spleen, lymph node, perivascular macrophages in brain and lower levels in bone marrow, liver Kupffer cells and lamina propria of colon and lung. Also expressed by inflammatory macrophages in rheumatoid arthritis. -
序列相似性
Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.
Contains 16 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
细胞定位
Secreted and Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 20612 Mouse
- SwissProt: Q62230 Mouse
- Unigene: 1374 Mouse
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别名
- CD169 antibody
- CD169 antigen antibody
- dJ1009E24.1 antibody
see all
图片
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Flow Cytometry - APC Anti-Sialoadhesin/CD169 antibody [EPR27102-11] (ab317480)
Flow cytometric analysis of Mouse bone marrow cells cells labelling Sialoadhesin/CD169 with AB317480 at 1/5000 dilution (0.01ug) / Right compared with a Rabbit IgG monoclonal [EPR25A] - Isotype Control (Allophycocyanin) (ab232814) / Left isotype control.
Gated on viable cell. Mouse bone marrow cells are co-stained with CD3 conjugated Alexa Fluor®488.
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![Flow Cytometry - APC Anti-Sialoadhesin/CD169 antibody [EPR27102-11] (ab317480)](https://www.abcam.cn/ps/products/317/ab317480/Images/ab317480-2-apc-anti-sialoadhesincd169-antibody-epr27102-11-flow-cytometry-mouse-bone-marrow-cells1.jpg)
Flow Cytometry - APC Anti-Sialoadhesin/CD169 antibody [EPR27102-11] (ab317480)Flow cytometric analysis of Mouse bone marrow cells cells labelling Sialoadhesin/CD169 with AB317480 at 1/5000 dilution (0.01ug) / Right compared with a Rabbit IgG monoclonal [EPR25A] - Isotype Control (Allophycocyanin) (ab232814) / Left isotype control.
Gated on viable cell. Mouse bone marrow cells are co-stained with F4/80 conjugated PE.
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![APC Anti-Sialoadhesin/CD169 antibody [EPR27102-11] (ab317480)](https://www.abcam.cn/ps/products/317/ab317480/Images/ab317480-3-Benefits-of-Recombinant-antibodies.jpg)
APC Anti-Sialoadhesin/CD169 antibody [EPR27102-11] (ab317480)
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab317480 尚未被引用在任何文献中。