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AB25486

APC Anti-IL-2 Receptor alpha抗体[7D4]

APC Anti-IL-2 Receptor alpha antibody [7D4]

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(4 Publications)

Rat Monoclonal IL2RA antibody - conjugated to APC. Suitable for Flow Cyt and reacts with Mouse samples. Cited in 4 publications. Immunogen corresponding to Cell preparation containing Il2ra protein.

查看别名

CD25, Il2r, Il2ra, Interleukin-2 receptor subunit alpha, IL-2 receptor subunit alpha, IL-2-RA, IL-2R subunit alpha, IL2-RA, p55

1 Images
Flow Cytometry - APC Anti-IL-2 Receptor alpha antibody [7D4] (AB25486)
  • Flow Cyt

Supplier Data

Flow Cytometry - APC Anti-IL-2 Receptor alpha antibody [7D4] (AB25486)

Con-A stimulated BALB/c mouse splenocytes were stained with Rat Anti- Mouse CD25-APC (ab25486). The grey peak represents an isotype control. The purple peak represents the positive dataset.

关键信息

宿主种属

Rat

克隆

Monoclonal

克隆号

7D4

亚型

IgM

轻链类型

kappa

偶联物

APC

激发波长/发射波长

Ex: 650nm, Em: 660nm

不含载体蛋白

No

反应种属

Mouse

应用

Flow Cyt

applications

免疫原

Cell preparation containing Il2ra protein. The exact immunogen used to generate this antibody is proprietary information.

P01590

表位

ab25486 reacts with an epitope between amino acids 125 and 212.

特异性

ab25486 reacts with the low affinity alpha chain IL-2 receptor (IL-2Ralpha).

反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "0.2 µg for 10^6 Cells", "FlowCyt-species-notes": "<p></p>" } } }

性能和储存信息

形式
Liquid
纯度
IgM fraction
存储溶液
pH: 7.3 Preservative: 0.09% Sodium azide Constituents: PBS, 16% Sucrose
运输条件
Blue Ice
推荐的短期储存条件
+4°C
推荐的长期储存条件
+4°C
储存信息
Store in the dark

产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

靶点信息

Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells.
See full target information Il2ra

文献 (4)

Recent publications for all applications. Explore the full list and refine your search

Journal of immunology (Baltimore, Md. : 1950) 185:956-66 PubMed20548032

2010

Synergistic antitumor effects of regulatory T cell blockade combined with pemetrexed in murine malignant mesothelioma.

Applications

Flow Cyt

Species

Mouse

Masaki Anraku,Tetsuzo Tagawa,Licun Wu,Zhihong Yun,Shaf Keshavjee,Li Zhang,Michael R Johnston,Marc de Perrot

Journal of immunology (Baltimore, Md. : 1950) 147:2970-7 PubMed1717581

1991

Structure-function study of the p55 subunit of murine IL-2 receptor by epitope mapping.

Applications

Unspecified application

Species

Unspecified reactive species

F Lorenzo,C Jaulin,N Vita,P Froussard,P Ferrara,D L Jankovic,J Theze

European journal of immunology 17:929-35 PubMed2440696

1987

Monoclonal antibodies identify three epitope clusters on the mouse p55 subunit of the interleukin 2 receptor: relationship to the interleukin 2-binding site.

Applications

Unspecified application

Species

Unspecified reactive species

J L Moreau,M Nabholz,T Diamantstein,T Malek,E Shevach,J Thèze

Journal of immunology (Baltimore, Md. : 1950) 133:1970-5 PubMed6206144

1984

The murine IL 2 receptor. I. Monoclonal antibodies that define distinct functional epitopes on activated T cells and react with activated B cells.

Applications

Unspecified application

Species

Unspecified reactive species

G Ortega,R J Robb,E M Shevach,T R Malek
View all publications

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