APC Anti-CD23抗体[2G8] (ab25457)
![Flow Cytometry - APC Anti-CD23 antibody [2G8] (ab25457)](https://www.abcam.cn/ps/products/25/ab25457/Images/ab25457-1-ab25457FC.jpg "Flow Cytometry - APC Anti-CD23 antibody [2G8] (ab25457)")
Key features and details
- APC Rat monoclonal [2G8] to CD23
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: APC. Ex: 645nm, Em: 660nm
- Isotype: IgG2a
概述
-
产品名称
APC Anti-CD23抗体[2G8]
参阅全部 CD23 一抗 -
描述
APC大鼠单克隆抗体[2G8] to CD23 -
宿主
Rat -
偶联物
APC. Ex: 645nm, Em: 660nm -
特异性
ab25457 recognises CD23 low affinity IgE Fc receptor. -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Mouse -
免疫原
Tissue, cells or virus corresponding to CD23. FcεR isolated from B cell lymphoma cell line M12.4.5
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. Store In the Dark. -
存储溶液
pH: 7.3
Preservative: 0.09% Sodium azide
Constituents: PBS, 16% Sucrose
Stabilising agent. -
Concentration information loading... -
纯度
Affinity purified -
克隆
单克隆 -
克隆编号
2G8 -
同种型
IgG2a -
轻链类型
kappa -
研究领域
相关产品
-
Alternative Versions
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab25457于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| Flow Cyt |
| 说明 |
|---|
Note: ab25457 can be used for identification and enumeration of CD23+ cells by flow cytometry and for differentiation of B cell subpopulations by cell sorting.
IP: Use at an assay dependent dilution.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
靶标
-
功能
This receptor has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen). -
序列相似性
Contains 1 C-type lectin domain. -
翻译后修饰
N- and O-glycosylated. -
细胞定位
Cell membrane. Secreted. Also exists as a soluble excreted form. - Information by UniProt
-
数据库链接
- Entrez Gene: 14128 Mouse
- SwissProt: P20693 Mouse
-
别名
- Blast 2 antibody
- BLAST-2 antibody
- Blast2 antibody
see all
图片
-
Flow Cytometry - APC Anti-CD23 antibody [2G8] (ab25457)
Flow cytometry analysis of BALB/c mouse splenocytes labeling CD23 with ab25457 at 0.1 µg/106cells and CD3 epsilon with Rat Anti-Mouse CD3 epsilon-FITC.
数据表及文件
-
SDS download
-
Datasheet download
文献 (1)
ab25457 被引用在 1 文献中.
- Hamel K et al. Suppression of Proteoglycan-Induced Arthritis by Anti-CD20 B Cell Depletion Therapy Is Mediated by Reduction in Autoantibodies and CD4+ T Cell Reactivity. J Immunol 180:4994-5003 (2008). Flow Cyt ; Mouse . PubMed: 18354225