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APC Anti-CD14抗体[MEM-15] (ab60901)

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Flow Cytometry - APC Anti-CD14 antibody [MEM-15] (ab60901)

    Key features and details

    • APC Mouse monoclonal [MEM-15] to CD14
    • Suitable for: Flow Cyt
    • Reacts with: Human
    • Conjugation: APC. Ex: 645nm, Em: 660nm
    • Isotype: IgG1

    概述

    • 产品名称

      APC Anti-CD14抗体[MEM-15]
      参阅全部 CD14 一抗

    • 描述

      APC小鼠单克隆抗体[MEM-15] to CD14

    • 宿主

      Mouse

    • 偶联物

      APC. Ex: 645nm, Em: 660nm

    • 特异性

      This antibody reacts with CD14, a membrane bound glycoprotein. The antibody also reacts with soluble forms of CD14 found in serum and in the urine of some nephrotic patients.

    • 经测试应用

      适用于: Flow Cytmore details

    • 种属反应性

      与反应: Human

    • 免疫原

      A crude mixture of human urinary proteins precipitated by ammonium sulphate from the urine of a patient suffering from proteinuria.

    • 阳性对照

      • Human blood cells

    • 常规说明

      Avoid prolonged exposure to light. Short-term exposure to room temperature should not affect the quality of the reagent.

      The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions.

      The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

      If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

    性能

    应用

    The Abpromise guarantee

    Abpromise™承诺保证使用ab60901于以下的经测试应用

    “应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。

    应用 Ab评论 说明
    Flow Cyt
    Use 10µl for 106 cells.

    Use 10µl per 100µl of whole blood or 106 cells in a suspension.
    说明
    Flow Cyt
    Use 10µl for 106 cells.

    Use 10µl per 100µl of whole blood or 106 cells in a suspension.

    靶标

    • 功能

      Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.

    • 组织特异性

      Expressed strongly on the surface of monocytes and weakly on the surface of granulocytes; also expressed by most tissue macrophages.

    • 序列相似性

      Contains 11 LRR (leucine-rich) repeats.

    • 翻译后修饰

      N- and O- glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan.

    • 细胞定位

      Cell membrane.
    • Information by UniProt

    • 数据库链接

      • 别名

        • CD 14 antibody
        • CD_antigen=CD14 antibody
        • CD14 antibody
        • CD14 antigen antibody
        • CD14 molecule antibody
        • CD14_HUMAN antibody
        • LPS-R antibody
        • Mo2 antibody
        • Monocyte differentiation antigen CD14 antibody
        • Monocyte differentiation antigen CD14 urinary form antibody
        • Monocyte differentiation antigen CD14, membrane-bound form antibody
        • Myeloid cell specific leucine rich glycoprotein antibody
        • Myeloid cell-specific leucine-rich glycoprotein antibody
        see all

      图片

      • Flow Cytometry - APC Anti-CD14 antibody [MEM-15] (ab60901)
        Flow Cytometry - APC Anti-CD14 antibody [MEM-15] (ab60901)

        Surface staining of human peripheral blood cells with ab60901 at 4 μg/ml

      文献 (0)

      发表研究结果有使用 ab60901？请让我们知道，以便我们可以引用本数据表中的参考文章。

      ab60901 尚未被引用在任何文献中。

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