APC Anti-CD105抗体[MEM-226]，prediluted (ab60902)
Key features and details
- APC Mouse monoclonal [MEM-226] to CD105, prediluted
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: APC. Ex: 645nm, Em: 660nm
- Isotype: IgG2a
Related conjugates and formulations
概述
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产品名称
APC Anti-CD105抗体[MEM-226]，prediluted
参阅全部 CD105 一抗 -
描述
APC小鼠单克隆抗体[MEM-226] to CD105，prediluted -
宿主
Mouse -
偶联物
APC. Ex: 645nm, Em: 660nm -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Human -
免疫原
Recombinant Vaccinia virus containing the human CD105 cDNA.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.4
Preservative: 0.097% Sodium azide
Constituents: PBS, 0.2% BSA -
Concentration information loading... -
纯度
Size exclusion -
纯化说明
The antibody was purified by Protein A (G) affinity chromatography before conjugation. The conjugate was purified by size-exclusion chromatography and adjusted for direct use. -
克隆
单克隆 -
克隆编号
MEM-226 -
同种型
IgG2a -
研究领域
相关产品
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Alternative Versions
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab60902于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| Flow Cyt |
Use at an assay dependent concentration.
Use 10ul per 100ul of whole blood or 10^6 cells in a suspension. ab91364 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
| 说明 |
|---|
|
Flow Cyt
Use at an assay dependent concentration. Use 10ul per 100ul of whole blood or 10^6 cells in a suspension. ab91364 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
靶标
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功能
Major glycoprotein of vascular endothelium. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. -
组织特异性
Endoglin is restricted to endothelial cells in all tissues except bone marrow. -
疾病相关
Defects in ENG are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1) [MIM:187300, 108010]; also known as Osler-Rendu-Weber syndrome 1 (ORW1). HHT1 is an autosomal dominant multisystemic vascular dysplasia, characterized by recurrent epistaxis, muco-cutaneous telangiectases, gastro-intestinal hemorrhage, and pulmonary (PAVM), cerebral (CAVM) and hepatic arteriovenous malformations; all secondary manifestations of the underlying vascular dysplasia. Although the first symptom of HHT1 in children is generally nose bleed, there is an important clinical heterogeneity. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 2022 Human
- Omim: 131195 Human
- SwissProt: P17813 Human
- Unigene: 76753 Human
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别名
- AI528660 antibody
- AI662476 antibody
- CD 105 antibody
see all
数据表及文件
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SDS download
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Datasheet download
文献 (4)
ab60902 被引用在 4 文献中.
- Pennings I et al. Effect of donor variation on osteogenesis and vasculogenesis in hydrogel cocultures. J Tissue Eng Regen Med 13:433-445 (2019). PubMed: 30650247
- Spirig R et al. rIgG1 Fc Hexamer Inhibits Antibody-Mediated Autoimmune Disease via Effects on Complement and Fc?Rs. J Immunol 200:2542-2553 (2018). PubMed: 29531170
- Kurian L et al. Conversion of human fibroblasts to angioblast-like progenitor cells. Nat Methods 10:77-83 (2013). PubMed: 23202434
- McLean K et al. Human ovarian carcinoma–associated mesenchymal stem cells regulate cancer stem cells and tumorigenesis via altered BMP production. J Clin Invest 121:3206-19 (2011). Flow Cyt ; Human . PubMed: 21737876