重组Anti-Annexin A1/ANXA1抗体[rANXA1/4310] (ab273136)
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Annexin A1/ANXA1 antibody [rANXA1/4310] (ab273136)](https://www.abcam.cn/ps/products/273/ab273136/Images/ab273136-391402-AntiAnnexin-A1-ANXA1-antibody-rANXA1-4310-immunohistochemistry-tonsil-human.JPG "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Annexin A1/ANXA1 antibody [rANXA1/4310] (ab273136)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Mouse monoclonal [rANXA1/4310] to Annexin A1/ANXA1
- Suitable for: IHC-P
- Reacts with: Human
Related conjugates and formulations
概述
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产品名称
Anti-Annexin A1/ANXA1抗体[rANXA1/4310]
参阅全部 Annexin A1/ANXA1 一抗 -
描述
小鼠单克隆抗体[rANXA1/4310] to Annexin A1/ANXA1 -
宿主
Mouse -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human -
免疫原
Recombinant full length protein corresponding to Human Annexin A1/ANXA1 aa 1-350.
Database link: P04083 -
阳性对照
- IHC-P: Human tonsil tissue.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.2
Preservative: 0.05% Sodium azide
Constituents: PBS, 0.05% BSA -
Concentration information loading... -
纯度
Protein A/G purified -
克隆
单克隆 -
克隆编号
rANXA1/4310 -
同种型
IgG2a -
轻链类型
kappa -
研究领域
相关产品
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Alternative Versions
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab273136于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P |
Use a concentration of 1 - 2 µg/ml. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
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| 说明 |
|---|
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IHC-P
Use a concentration of 1 - 2 µg/ml. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol. |
靶标
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功能
Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity. -
序列相似性
Belongs to the annexin family.
Contains 4 annexin repeats. -
结构域
A pair of annexin repeats may form one binding site for calcium and phospholipid. -
翻译后修饰
Phosphorylated by protein kinase C, epidermal growth factor receptor/kinase and TRPM7. Phosphorylation results in loss of the inhibitory activity. -
细胞定位
Nucleus. Cytoplasm. Cell projection > cilium. Basolateral cell membrane. Found in the cilium, nucleus and basolateral cell membrane of ciliated cells in the tracheal endothelium (By similarity). Found in the cytoplasm of type II pneumocytes and alveolar macrophages. - Information by UniProt
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数据库链接
- Entrez Gene: 301 Human
- Omim: 151690 Human
- SwissProt: P04083 Human
- Unigene: 494173 Human
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别名
- Annexin 1 antibody
- Annexin A1 antibody
- Annexin I (lipocortin I) antibody
see all
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Annexin A1/ANXA1 antibody [rANXA1/4310] (ab273136)
Paraffin embedded human tonsil tissue stained for Annexin A1 using ab273136 at 2 µg/ml in immunohistochemical analysis.
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![Anti-Annexin A1/ANXA1 antibody [rANXA1/4310] (ab273136)](https://www.abcam.cn/ps/products/273/ab273136/Images/ab273136-2-benefits-of-recombinant-antibodies.png)
Anti-Annexin A1/ANXA1 antibody [rANXA1/4310] (ab273136)
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab273136 尚未被引用在任何文献中。