Anti-Angiopoietin 2/ANG2抗体(ab125692)
Key features and details
- Rabbit polyclonal to Angiopoietin 2/ANG2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术，可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-Angiopoietin 2/ANG2抗体
参阅全部 Angiopoietin 2/ANG2 一抗 -
描述
兔多克隆抗体to Angiopoietin 2/ANG2 -
宿主
Rabbit -
特异性
At least three isoforms of ANGPT2 are known to exist; this antibody will detect all three isoforms. -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide corresponding to Human Angiopoietin 2/ANG2 (C terminal).
(Peptide available asab172727) -
阳性对照
- WB: Human Liver Tissue Lysate.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab125692于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 56 kDa.
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| 说明 |
|---|
|
WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 56 kDa. |
靶标
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功能
Can induce tyrosine phosphorylation of TIE2. Binds to TIE2 receptor and counteracts blood vessel maturation/stability mediated by angiopoietin-1. Its function may be context-dependent. In the absence of angiogenic inducers, such as VEGF, ANG2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal. -
序列相似性
Contains 1 fibrinogen C-terminal domain. -
结构域
The Fibrinogen C-terminal domain mediates interaction with the TEK/TIE2 receptor. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 285 Human
- Omim: 601922 Human
- SwissProt: O15123 Human
- Unigene: 583870 Human
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别名
- AGPT 2 antibody
- Agpt2 antibody
- ANG 2 antibody
see all
图片
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Western blot - Anti-Angiopoietin 2/ANG2 antibody (ab125692)Lane 1 : Anti-Angiopoietin 2/ANG2 antibody (ab125692) at 1 µg/ml
Lane 2 : Anti-Angiopoietin 2/ANG2 antibody (ab125692) at 2 µg/ml
All lanes : Human liver tissue lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 56 kDa
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab125692 被引用在 2 文献中.
- Feng XF et al. Tetramethylpyrazine promotes stroke recovery by inducing the restoration of neurovascular unit and transformation of A1/A2 reactive astrocytes. Front Cell Neurosci 17:1125412 (2023). PubMed: 37051111
- Zhan Y et al. An MRI Study of Neurovascular Restorative After Combination Treatment With Xiaoshuan Enteric-Coated Capsule and Enriched Environment in Rats After Stroke. Front Neurosci 13:701 (2019). PubMed: 31354412