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Neuroscience Neurology process Notch Pathway

Anti-Amyloid Fibril抗体(ab126468)

  • Datasheet
  • SDS
Submit a review Q&A (1)References (2)

Product price, shipping and contact information

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送货和订单信息

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Promotion Information

Abpromise

产品质量保证,客户专家支持,

点击获取更多

Key features and details

  • Rabbit polyclonal to Amyloid Fibril
  • Suitable for: WB, ELISA, Dot blot, IHC, IP, ICC/IF
  • Reacts with: Human
  • Isotype: IgG

选择批间可重复性更高的重组抗体

Product image
Anti-Amyloid Precursor Protein antibody [Y188] - Low endotoxin, Azide free (ab220793)
  • 研究可靠 —— 各批次间结果一致且可重复
  • 长期批量供应 —— 采用重组技术,可实现快速生产
  • 首次实验即可成功 —— 经过大量验证确认了特异性
  • 符合伦理标准 —— 产品不含动物成分

概述

  • 产品名称

    Anti-Amyloid Fibril抗体
    参阅全部 Amyloid Fibril 一抗
  • 描述

    兔多克隆抗体to Amyloid Fibril
  • 宿主

    Rabbit
  • 特异性

    Recognizes generic epitopes common to many amyloid fibrils and fibrillar oligomers, but not prefibrillar oligomers or natively folded proteins. Expected to detect in Mouse and Rat based on species homology.

  • 经测试应用

    适用于: WB, ELISA, Dot blot, IHC, IP, ICC/IFmore details
  • 种属反应性

    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Fibrils prepared from Human Aß42 peptide.

  • 常规说明

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

性能

  • 形式

    Liquid
  • 存放说明

    Shipped at 4°C. Store at -20ºC.
  • 存储溶液

    Preservative: 0.09% Sodium azide
    Constituents: 50% Glycerol (glycerin, glycerine), 49% PBS
  • Concentration information loading...
  • 纯度

    Protein A purified
  • 克隆

    多克隆
  • 同种型

    IgG
  • 研究领域

    • Neuroscience
    • Neurology process
    • Notch Pathway
    • Neuroscience
    • Cell Adhesion Proteins
    • Membrane Proteins
    • Cardiovascular
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    • Acute Phase Reactants
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相关产品

  • Compatible Secondaries

    • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
    • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
  • Isotype control

    • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)
  • Related Products

    • Anti-Amyloid Oligomers antibody (ab126892)

应用

The Abpromise guarantee

Abpromise™承诺保证使用ab126468于以下的经测试应用

“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。

应用 Ab评论 说明
WB
1/1000.
ELISA
Use at an assay dependent concentration.
Dot blot
Use at an assay dependent concentration.
IHC
1/100.
IP
Use at an assay dependent concentration.
ICC/IF
Use at an assay dependent concentration.
说明
WB
1/1000.
ELISA
Use at an assay dependent concentration.
Dot blot
Use at an assay dependent concentration.
IHC
1/100.
IP
Use at an assay dependent concentration.
ICC/IF
Use at an assay dependent concentration.

靶标

  • 细胞定位

    Membrane.
  • 数据库链接

    • Entrez Gene: 351 Human
    • Entrez Gene: 11820 Mouse
    • Entrez Gene: 54226 Rat
    • GenBank: 9606 Human
    • Omim: 104760 Human
    • SwissProt: P05067 Human
    • SwissProt: P12023 Mouse
    • SwissProt: P08592 Rat
    • 别名

      • AAA antibody
      • ABETA antibody
      • ABPP antibody
      • AD1 antibody
      • Alzheimer disease amyloid protein antibody
      • Amyloid beta precursor protein antibody
      • APP antibody
      • APPI antibody
      • Beta amyloid peptide antibody
      • Cerebral vascular amyloid peptide antibody
      • CTFgamma antibody
      • CVAP antibody
      • Peptidase nexin II antibody
      • PN II antibody
      • PN2 antibody
      • PreA4 antibody
      • Protease nexin II antibody
      see all

    实验方案

    • Immunohistochemistry protocols

    Click here to view the general protocols

    数据表及文件

    • SDS download

    • Datasheet download

      Download

    文献 (2)

    发表研究结果有使用 ab126468?请让我们知道,以便我们可以引用本数据表中的参考文章。

    ab126468 被引用在 2 文献中.

    • Chatterjee D  et al. Co-aggregation and secondary nucleation in the life cycle of human prolactin/galanin functional amyloids. Elife 11:N/A (2022). PubMed: 35257659
    • Peters F  et al. Tau deletion reduces plaque-associated BACE1 accumulation and decelerates plaque formation in a mouse model of Alzheimer's disease. EMBO J 38:e102345 (2019). PubMed: 31701556

    客户评价及客户问答

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    提交评价 提交问题

    Question

    Dear Abcam, As of 5-3-12 our lab has purchased the antibody ab126468. When I conducted a western blot with your antibody on Sprague Dawley Rat plasma samples the antibody did not produce a band at 14kDa. This was tested on many western blots with the same stock plasma. According to mass spectroscopy studies(ITRAQ) the protein serum amyloid fibril is in my plasma samples for Sprague Dawley Rats. We would appreciate if this antibody could be replaced and if not available we would appreciate a refund for this antibody from order reference number 1082422.

    Read More

    Abcam community

    Verified customer

    Asked on Oct 03 2012

    Answer

    Thank you for contacting Abcam.

    As we have not tested ab126468 in rat samples, we could not guarantee that it would work for that species. Therefore under the terms of out Abpromise, I am unable to repalce or refund the antibody for you.

    What I could do though, is to issue a back dated Testing Discount code for you. What this means is that if you submit an Abreview on how the antibody work on rat samples, plus an image, then once the Abreview has been submitted, you will be able to use the code to get any primary antibody from our catalogue, free of charge.

    If you are interested in submitting an Abreview, then please let me know and I will be happy to issue you the discount code.

    I look forward to your reply.

    Read More

    Abcam Scientific Support

    回复于 Oct 03 2012

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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