Anti-AMG抗体(ab153915)
Key features and details
- Rabbit polyclonal to AMG
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
概述
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产品名称
Anti-AMG抗体 -
描述
兔多克隆抗体to AMG -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Mouse, Human
预测可用于: Monkey
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免疫原
Recombinant fragment corresponding to Human AMG aa 1-191.
Database link: Q99217 -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 79.99% PBS, 20% Glycerol (glycerin, glycerine) -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab153915于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/500 - 1/3000. Predicted molecular weight: 22 kDa.
|
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| IHC-P | (2) |
Use at an assay dependent concentration. PubMed: 29089903
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| 说明 |
|---|
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WB
1/500 - 1/3000. Predicted molecular weight: 22 kDa. |
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IHC-P
Use at an assay dependent concentration. PubMed: 29089903 |
靶标
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功能
Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel. -
疾病相关
Defects in AMELX are the cause of amelogenesis imperfecta hypoplastic type 1 (AIH1) [MIM:301200]. AIH1 is a X-linked defect of dental enamel formation. Teeth have only a thin layer of enamel with normal hardness. The thinness of the enamel makes the teeth appear small. -
序列相似性
Belongs to the amelogenin family. -
发展阶段
Transiently but abundantly expressed by ameloblasts during tooth development. Amelogenin is the predominant protein in developing dental enamel. -
细胞定位
Secreted > extracellular space > extracellular matrix. - Information by UniProt
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数据库链接
- Entrez Gene: 265 Human
- Entrez Gene: 11704 Mouse
- Omim: 300391 Human
- SwissProt: Q99217 Human
- SwissProt: P63277 Mouse
- Unigene: 654436 Human
- Unigene: 391342 Mouse
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别名
- AI1E antibody
- AIH1 antibody
- ALGN antibody
see all
图片
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Western blot - Anti-AMG antibody (ab153915)Anti-AMG antibody (ab153915) at 1/500 dilution + NIH 3T3 whole cell lysate at 30 µg
Predicted band size: 22 kDa
12% SDS PAGE -
Western blot - Anti-AMG antibody (ab153915)Anti-AMG antibody (ab153915) at 1/500 dilution + Jurkat whole cell lysate at 30 µg
Predicted band size: 22 kDa
12% SDS PAGE
数据表及文件
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SDS download
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Datasheet download
文献 (13)
ab153915 被引用在 13 文献中.
- Said R et al. Deciphering the functions of Stromal Interaction Molecule-1 in amelogenesis using AmelX-iCre mice. Front Physiol 14:1100714 (2023). PubMed: 36935757
- Mitsiadis TA et al. Notch Signaling Pathway in Tooth Shape Variations throughout Evolution. Cells 12:N/A (2023). PubMed: 36899896
- Lee ES et al. The effects of 4-Phenylbutyric acid on ER stress during mouse tooth development. Front Physiol 13:1079355 (2022). PubMed: 36685173
- Bazina F et al. Partial epithelial-mesenchymal transition during enamel development. Clin Exp Dent Res 8:513-518 (2022). PubMed: 35182458
- Suzuki A et al. Crucial Roles of microRNA-16-5p and microRNA-27b-3p in Ameloblast Differentiation Through Regulation of Genes Associated With Amelogenesis Imperfecta. Front Genet 13:788259 (2022). PubMed: 35401675