Anti-ALS2CL抗体(ab119937)
Key features and details
- Rabbit polyclonal to ALS2CL
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
概述
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产品名称
Anti-ALS2CL抗体
参阅全部 ALS2CL 一抗 -
描述
兔多克隆抗体to ALS2CL -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Mouse -
免疫原
Synthetic peptide from N terminal residues of Human ALS2CL protein (NM_147129.3).
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阳性对照
- Mouse kidney lysate.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Lyophilized:Reconstitute in 200ul sterile H2O. -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading... -
纯度
Immunogen affinity purified -
纯化说明
ab119937 is purified by a peptide affinity column. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab119937于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/500 - 1/1000. Detects a band of approximately 108 kDa (predicted molecular weight: 22, 23, 53, 85, 108 kDa).
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| 说明 |
|---|
|
WB
1/500 - 1/1000. Detects a band of approximately 108 kDa (predicted molecular weight: 22, 23, 53, 85, 108 kDa). |
靶标
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功能
Acts as a guanine nucleotide exchange factor (GEF) for Rab5 GTPase. Regulates the ALS2-mediated endosome dynamics. -
组织特异性
Expressed in heart and kidney. -
序列相似性
Contains 8 MORN repeats.
Contains 1 VPS9 domain. -
细胞定位
Cytoplasm. Distributed onto the vesicular compartments in the cytoplasm with strong punctated staining. Colocalizes with RAB5A onto the vesicular/membranous compartments in the cytoplasm, particularly to the leading edges of the cells. - Information by UniProt
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数据库链接
- Entrez Gene: 235633 Mouse
- SwissProt: Q60I26 Mouse
- Unigene: 86338 Mouse
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别名
- AL2CL_HUMAN antibody
- ALS2 C-terminal like antibody
- ALS2 C-terminal-like protein antibody
see all
图片
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Western blot - Anti-ALS2CL antibody (ab119937)Anti-ALS2CL antibody (ab119937) at 1/500 dilution + Mouse kidney lysate
Predicted band size: 22, 23, 53, 85, 108 kDa
Observed band size: 108 kDa why is the actual band size different from the predicted?
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab119937 尚未被引用在任何文献中。