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AB112972

Anti-alpha Lactalbumin 抗体

Anti-alpha Lactalbumin antibody

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(2 Publications)

Goat Polyclonal alpha Lactalbumin antibody. Suitable for ICC, ELISA, WB, IHC-P and reacts with Cow samples. Cited in 2 publications.

查看别名

ALACTA, LALBA, Alpha-lactalbumin, Lactose synthase B protein

关键信息

宿主种属

Goat

克隆

Polyclonal

亚型

IgG

不含载体蛋白

No

反应种属

Cow

应用

ICC, WB, ELISA, IHC-P

applications

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替代产品

Primary Antibodies

AB180180

Anti-alpha Lactalbumin antibody [EPR12461]

RabMAb|Recombinant

Western blot - Anti-alpha Lactalbumin antibody [EPR12461] (AB180180)

  • 0
  • 0
Primary Antibodies

AB20212

Anti-alpha Lactalbumin antibody [F20.16]

Immunocytochemistry/ Immunofluorescence - Anti-alpha Lactalbumin antibody [F20.16] (AB20212)

  • 0
  • 0
Primary Antibodies

AB112973

HRP Anti-alpha Lactalbumin antibody

  • 0
  • 0
Primary Antibodies

AB178431

Anti-alpha Lactalbumin antibody [EPR12460]

RabMAb|Recombinant

Western blot - Anti-alpha Lactalbumin antibody [EPR12460] (AB178431)

  • 0
  • 0

搭配使用产品

Primary Antibodies

AB166596

Anti-Casein antibody

Western blot - Anti-Casein antibody (AB166596)

  • 5
  • 2
Primary Antibodies

AB205301

Anti-beta Casein antibody [EPR12179]

RabMAb|Recombinant

Immunoprecipitation - Anti-beta Casein antibody [EPR12179] (AB205301)

  • 4
  • 3
Primary Antibodies

AB121326

Anti-B4GALT1 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-B4GALT1 antibody (AB121326)

  • 5
  • 2
Primary Antibodies

AB52649

Anti-GM130 antibody [EP892Y] - cis-Golgi Marker

RabMAb|Recombinant|Lab Essentials|20ul selling size

Immunoprecipitation - Anti-GM130 antibody [EP892Y] - cis-Golgi Marker (AB52649)

  • 5
  • 39
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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICC" : {"fullname" : "Immunocytochemistry", "shortname":"ICC"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Cow": { "ICC-species-checked": "guaranteed", "ICC-species-dilution-info": "", "ICC-species-notes": "<p></p>", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p>Coating: Use 1/100-1/500 dilution; Primary: Use 1/1000-1/30000 dilution.</p>", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p>Colorimetric: Use 1/1000-1/10000 dilution; Chemiluminescent: Use 1/1000-1/30000 dilution.</p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>" } } }
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性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Immunogen
纯化说明
Antiserum was solid phase adsorbed to ensure specificity. ab112972 was isolated by affinity chromatography using antigen coupled to agarose beads.
存储溶液
pH: 6.8 - 7.4 Preservative: 0.1% Sodium azide Constituents: PBS
运输条件
Blue Ice
推荐的短期储存条件
+4°C
推荐的长期储存条件
+4°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle|Do Not Freeze
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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

Alpha-lactalbumin commonly known as lactalbumin or alpha-lactoglobulin has a mass of approximately 14.2 kDa. This protein is mainly expressed in the mammary glands of mammals where it serves an important function in lactose synthesis. It modifies the action of galactosyltransferase an enzyme to enable the transfer of sugar units resulting in the production of lactose. The biochemical role of this lactalbumin protein including its unique structure is important in adapting the lactation system to meet the nutritional needs of offspring.
Biological function summary

Alpha-lactalbumin's role is closely linked to the synthesis and secretion of milk. It functions as part of the lactose synthase complex which is essential for converting glucose to lactose. This conversion is important because lactose dictates milk osmotic pressure affecting milk volume and overall composition. In addition to its primary role in milk production this protein structure supports various cellular processes due to its ability to bind calcium and other ions.

Pathways

Alpha-lactalbumin participates mainly in the lactose synthesis pathway. In this metabolic map it interacts extensively with other proteins involved in milk production particularly beta-14-galactosyltransferase. This interaction enhances the efficiency of lactose production. Its presence in these pathways epitomizes the close relationship and cellular coordination needed for effective lactose synthesis during lactation.

Researchers have identified connections between alpha-lactalbumin and breast cancer as well as lactose intolerance. Changes in the expression levels of this protein can impact the development and regulation of tumors in breast tissue linked to interactions with proteins such as casein. Furthermore variants of alpha-lactalbumin can affect individuals with lactose intolerance where the protein's role in regulating lactose production must be managed to alleviate symptoms.
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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:
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靶点信息

Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins.
See full target information LALBA
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文献 (2)

Recent publications for all applications. Explore the full list and refine your search

Alimentary pharmacology & therapeutics 53:410-417 PubMed33264440

2020

Mucosal penetration and clearance of gluten and milk antigens in eosinophilic oesophagitis.

Applications

Unspecified application

Species

Unspecified reactive species

Anupama Ravi,Eric V Marietta,Jeffrey A Alexander,Kathryn Peterson,Crystal Lavey,Debra M Geno,Joseph A Murray,David A Katzka

The Journal of reproduction and development 61:145-53 PubMed25740096

2015

Collagen complexes increase the efficiency of iPS cells generated using fibroblasts from adult mice.

Applications

Unspecified application

Species

Unspecified reactive species

Byung-Soo Chang,Yun-Jung Choi,Jin-Hoi Kim
View all publications
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