重组Anti-ALG2抗体[EPR12006(2)(B)] (ab178697)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR12006(2)(B)] to ALG2
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
概述
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产品名称
Anti-ALG2抗体[EPR12006(2)(B)]
参阅全部 ALG2 一抗 -
描述
兔单克隆抗体[EPR12006(2)(B)] to ALG2 -
宿主
Rabbit -
经测试应用
适用于: WBmore details
不适用于: Flow Cyt,ICC/IF,IHC-P or IP -
种属反应性
与反应: Human -
免疫原
Synthetic peptide within Human ALG2 aa 1-100 (Cysteine residue). The exact sequence is proprietary.
Database link: Q9H553 -
阳性对照
- HepG2, HeLa, A431 and Human fetal kidney lysates.
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常规说明
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading...
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纯度
Tissue culture supernatant -
克隆
单克隆 -
克隆编号
EPR12006(2)(B) -
同种型
IgG -
研究领域
相关产品
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Alternative Versions
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab178697于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB |
1/10000 - 1/50000. Predicted molecular weight: 47 kDa.
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说明 |
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WB
1/10000 - 1/50000. Predicted molecular weight: 47 kDa. |
靶标
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功能
Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. -
通路
Protein modification; protein glycosylation. -
疾病相关
Defects in ALG2 are the cause of congenital disorder of glycosylation type 1I (CDG1I) [MIM:607906]. CDGs are a family of severe inherited diseases caused by a defect in protein N-glycosylation. They are characterized by under-glycosylated serum proteins. These multisystem disorders present with a wide variety of clinical features, such as disorders of the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency. The broad spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation, and maintenance of cell functions. -
序列相似性
Belongs to the glycosyltransferase 1 family. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 85365 Human
- Omim: 607905 Human
- SwissProt: Q9H553 Human
- Unigene: 40919 Human
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别名
- 3-mannosyltransferase ALG2 antibody
- ALG2 alpha-1,3/1,6-mannosyltransferase antibody
- ALG2 antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab178697 尚未被引用在任何文献中。