Alexa Fluor® 750 Anti-TROP2 antibody [SP293] - C-terminal
Alexa Fluor® 750 Anti-TROP2 antibody [SP293] - C-terminal
- Recombinant
- RabMAb
- 了解详情
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Rabbit Recombinant Monoclonal TROP2 antibody - conjugated to Alexa Fluor® 750.
查看别名
GA733-1, M1S1, TROP2, TACSTD2, Tumor-associated calcium signal transducer 2, Cell surface glycoprotein Trop-2, Membrane component chromosome 1 surface marker 1, Pancreatic carcinoma marker protein GA733-1
不同偶联物与剂型 (10)
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Anti-TROP2 antibody [SP293] - C-terminal
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Anti-TROP2 antibody [SP293] - BSA and Azide free
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578 PE
PE Anti-TROP2 antibody [SP293] (C-terminal)
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660 APC
APC Anti-TROP2 antibody [SP293] (C-terminal)
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HRP Anti-TROP2 antibody [SP293] (C-terminal)
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519 Alexa Fluor® 488
Alexa Fluor® 488 Anti-TROP2 antibody [SP293] - C-terminal
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665 Alexa Fluor® 647
Alexa Fluor® 647 Anti-TROP2 antibody [SP293] - C-terminal
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617 Alexa Fluor® 594
Alexa Fluor® 594 Anti-TROP2 antibody [SP293] - C-terminal
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565 Alexa Fluor® 555
Alexa Fluor® 555 Anti-TROP2 antibody [SP293] - C-terminal
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603 Alexa Fluor® 568
Alexa Fluor® 568 Anti-TROP2 antibody [SP293] - C-terminal
产品详情
Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free batch production
For more information, read more on recombinant antibodies.
How are conjugated primary antibodies validated?
This conjugated primary antibody is released using a quantitative quality control method that evaluates binding affinity post-conjugation and efficiency of antibody labeling.
For suitable applications and species reactivity, please refer to the unconjugated version of this clone.
Alexa Fluor® is a registered trademark of Molecular Probes, Inc, a Thermo Fisher Scientific Company. The Alexa Fluor® dye included in this product is provided under an intellectual property license from Life Technologies Corporation. As this product contains the Alexa Fluor® dye, the purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). As this product contains the Alexa Fluor® dye the sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: in manufacturing; (ii) to provide a service, information, or data in return for payment (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are sold for use in research. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.
性能和储存信息
形式
纯化工艺
存储溶液
运输条件
推荐的短期储存时间
推荐的短期储存条件
推荐的长期储存条件
分装信息
储存信息
补充信息
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
TROP2 mediates calcium signaling and cell proliferation. It functions by being a part of a signaling complex on the cell membrane which affects multiple cellular activities such as cell growth motility and survival. Its role in maintaining the integrity of the epithelial cell layer also shows TROP2's significance in normal tissue homeostasis. The interaction of TROP2 with the extracellular matrix and other cell surface proteins support the structural integrity and communication between cells.
Pathways
TROP2 plays a central role in the PI3K/AKT and MAPK signaling pathways that regulate cell growth and survival. Within these pathways TROP2 works in concert with proteins like ERK and AKT important for transmitting extracellular signals into appropriate cellular responses. These pathways are key regulators of many physiological processes including cell cycle progression and apoptosis prevention.
产品实验方案
- Visit the General protocols
- Visit the Troubleshooting
Abcam Product Promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com