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AB312535

重组Alexa Fluor® 568荧光Anti-PSMD9抗体[EPR12947]

Alexa Fluor® 568 Anti-PSMD9 antibody [EPR12947]

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Rabbit Recombinant Monoclonal PSMD9 antibody - conjugated to Alexa Fluor® 568.

查看别名

26S proteasome non-ATPase regulatory subunit 9, 26S proteasome regulatory subunit p27, PSMD9

不同偶联物与剂型 (10)

  • 660 APC

    APC Anti-PSMD9 antibody [EPR12947]

  • HRP

    HRP Anti-PSMD9 antibody [EPR12947]

  • 665 Alexa Fluor® 647

    Alexa Fluor® 647 Anti-PSMD9 antibody [EPR12947]

  • Unconjugated

    Anti-PSMD9 antibody [EPR12947]

  • 578 PE

    PE Anti-PSMD9 antibody [EPR12947]

  • 617 Alexa Fluor® 594

    Alexa Fluor® 594 Anti-PSMD9 antibody [EPR12947]

  • 519 Alexa Fluor® 488

    Alexa Fluor® 488 Anti-PSMD9 antibody [EPR12947]

  • 565 Alexa Fluor® 555

    Alexa Fluor® 555 Anti-PSMD9 antibody [EPR12947]

  • 775 Alexa Fluor® 750

    Alexa Fluor® 750 Anti-PSMD9 antibody [EPR12947]

  • Carrier free

    Anti-PSMD9 antibody [EPR12947] - BSA and Azide free

关键信息

宿主种属

Rabbit

克隆

Monoclonal

克隆号

EPR12947

亚型

IgG

偶联物

Alexa Fluor® 568

激发波长/发射波长

Ex: 578nm, Em: 603nm

不含载体蛋白

No

应用

Antibody Labelling, Target Binding Affinity

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

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为什么推荐这个?

我们推荐这个产品,因为它经常被用于相同的实验或相关的研究。

我们建议您务必查阅产品说明书,以确认其是否符合您的实验需求;若有疑问,也可联系我们的技术团队获取协助。

产品详情

性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Protein A
存储溶液
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: 68% PBS, 30% Glycerol (glycerin, glycerine), 1% BSA
运输条件
Blue Ice
推荐的短期储存时间
1-2 weeks
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle|Store in the dark

补充信息

This supplementary information is collated from multiple sources and compiled automatically.

PSMD9 also known as 26S proteasome non-ATPase regulatory subunit 9 or Bridge-1 is a component of the 26S proteasome complex. This protein has a mass of approximately 49 kDa. It plays a role in regulating the degradation of ubiquitinated proteins through its function in the proteasome complex. The protein is expressed in multiple tissues including skeletal muscle and heart.
Biological function summary

PSMD9 participates in proteasomal degradation of intracellular proteins facilitating protein turnover and maintaining cellular homeostasis. It integrates into the 26S proteasome complex consisting of the 20S core particle and the 19S regulatory particle. Within the proteasome PSMD9 interacts with various subunits to regulate the recognition and unfolding of ubiquitinated substrates.

Pathways

PSMD9 plays an important role in the ubiquitin-proteasome pathway which is essential for protein regulation and quality control in cells. This pathway involves tagging proteins with ubiquitin for degradation. PSMD9 shows functional relationships with other proteasome subunits like PSMD4 and PSMD11 which participate in similar regulation processes.

Dysfunction of the ubiquitin-proteasome pathway involving PSMD9 contributes to neurodegenerative diseases such as Alzheimer's disease and certain types of cancer. In Alzheimer's improper proteasomal activity can lead to the accumulation of damaged proteins. PSMD9's activity links it to other proteins implicated in these diseases including PSMD1 and the amyloid precursor protein in Alzheimer's disease.

产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

靶点信息

Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC). During the base subcomplex assembly is part of an intermediate PSMD9 : PSMC6 : PSMC3 module, also known as modulator trimer complex; PSMD9 is released during the further base assembly process.
See full target information 26S proteasome non-ATPase regulatory subunit 9

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详情请参阅我们的条款与条件。

关联产品

Select an associated product type
Alternative Version
Primary Antibodies

AB250563

Anti-PSMD9 antibody [EPR12947] - BSA and Azide free

primary-antibodies

psmd9-antibody-epr12947-bsa-and-azide-free-ab250563

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(0 reviews)

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