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AB312941

重组Alexa Fluor® 568荧光Anti-Melanoma gp100抗体[EP4863(2)]

Alexa Fluor® 568 Anti-Melanoma gp100 antibody [EP4863(2)]

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Rabbit Recombinant Monoclonal Melanoma gp100 antibody - conjugated to Alexa Fluor® 568.

查看别名

D12S53E, PMEL17, SILV, PMEL, Melanocyte protein PMEL, ME20-M, Melanocyte protein Pmel 17, Melanocytes lineage-specific antigen GP100, Melanoma-associated ME20 antigen, P1, P100, Premelanosome protein, Silver locus protein homolog, ME20M

不同偶联物与剂型 (10)

  • 578 PE

    PE Anti-Melanoma gp100 antibody [EP4863(2)]

  • HRP

    HRP Anti-Melanoma gp100 antibody [EP4863(2)]

  • Biotin

    Biotin Anti-Melanoma gp100 antibody [EP4863(2)]

  • 665 Alexa Fluor® 647

    Alexa Fluor® 647 Anti-Melanoma gp100 antibody [EP4863(2)]

  • 660 APC

    APC Anti-Melanoma gp100 antibody [EP4863(2)]

  • 617 Alexa Fluor® 594

    Alexa Fluor® 594 Anti-Melanoma gp100 antibody [EP4863(2)]

  • 565 Alexa Fluor® 555

    Alexa Fluor® 555 Anti-Melanoma gp100 antibody [EP4863(2)]

  • Unconjugated

    Anti-Melanoma gp100 antibody [EP4863(2)]

  • Carrier free

    Anti-Melanoma gp100 antibody [EP4863(2)] - Low endotoxin, Azide free

  • Carrier free

    Anti-Melanoma gp100 antibody [EP4863(2)] - BSA and Azide free

关键信息

宿主种属

Rabbit

克隆

Monoclonal

克隆号

EP4863(2)

亚型

IgG

偶联物

Alexa Fluor® 568

激发波长/发射波长

Ex: 578nm, Em: 603nm

不含载体蛋白

No

应用

Antibody Labelling, Target Binding Affinity

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

特异性

The mouse recommendation is based on the WB results. We do not guarantee IHC-P for mouse.

产品详情

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

How are conjugated primary antibodies validated?
This conjugated primary antibody is released using a quantitative quality control method that evaluates binding affinity post-conjugation and efficiency of antibody labeling.
For suitable applications and species reactivity, please refer to the unconjugated version of this clone.

性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Protein A
存储溶液
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 30% Glycerol (glycerin, glycerine), 1% BSA
运输条件
Blue Ice
推荐的短期储存时间
1-2 weeks
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle|Store in the dark

产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

靶点信息

Forms physiological amyloids that play a central role in melanosome morphogenesis and pigmentation. The maturation of unpigmented premelanosomes from stage I to II is marked by assembly of processed amyloidogenic fragments into parallel fibrillar sheets, which elongate the vesicle into a striated ellipsoidal shape. In pigmented stage III and IV melanosomes, the amyloid matrix serves as a platform where eumelanin precursors accumulate at high local concentrations for pigment formation. May prevent pigmentation-associated toxicity by sequestering toxic reaction intermediates of eumelanin biosynthesis pathway.. Represents a potent melanoma-specific antigen. Among melanoma non-mutated self-peptides, G9-154 (KTWGQYWQV), G9-209 (ITDQVPFSV) and G9-280 (YLEPGPVTA), appear to act as immunodominant common epitopes that stimulate anti-tumor immune response mediated by HLA-A-restricted cytotoxic T cells.
See full target information PMEL

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详情请参阅我们的条款与条件。

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