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AB312491

重组Alexa Fluor® 568荧光Anti-Extracellular matrix蛋白1抗体[EPR6701]

Alexa Fluor® 568 Anti-Extracellular matrix protein 1 antibody [EPR6701]

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Rabbit Recombinant Monoclonal Extracellular matrix protein 1 antibody - conjugated to Alexa Fluor® 568.

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Extracellular matrix protein 1, Secretory component p85, ECM1

不同偶联物与剂型 (10)

  • Unconjugated

    Anti-Extracellular matrix protein 1 antibody [EPR6701]

  • 578 PE

    PE Anti-Extracellular matrix protein 1 antibody [EPR6701]

  • 660 APC

    APC Anti-Extracellular matrix protein 1 antibody [EPR6701]

  • 617 Alexa Fluor® 594

    Alexa Fluor® 594 Anti-Extracellular matrix protein 1 antibody [EPR6701]

  • 519 Alexa Fluor® 488

    Alexa Fluor® 488 Anti-Extracellular matrix protein 1 antibody [EPR6701]

  • 565 Alexa Fluor® 555

    Alexa Fluor® 555 Anti-Extracellular matrix protein 1 antibody [EPR6701]

  • HRP

    HRP Anti-Extracellular matrix protein 1 antibody [EPR6701]

  • 665 Alexa Fluor® 647

    Alexa Fluor® 647 Anti-Extracellular matrix protein 1 antibody [EPR6701]

  • 775 Alexa Fluor® 750

    Alexa Fluor® 750 Anti-Extracellular matrix protein 1 antibody [EPR6701]

  • Carrier free

    Anti-Extracellular matrix protein 1 antibody [EPR6701] - BSA and Azide free

关键信息

宿主种属

Rabbit

克隆

Monoclonal

克隆号

EPR6701

亚型

IgG

偶联物

Alexa Fluor® 568

激发波长/发射波长

Ex: 578nm, Em: 603nm

不含载体蛋白

No

应用

Target Binding Affinity, Antibody Labelling

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

特异性

The rat recommendation is based on the WB results. We do not guarantee IHC-P for rat.

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为什么推荐这个?

我们推荐这个产品,因为它经常被用于相同的实验或相关的研究。

我们建议您务必查阅产品说明书,以确认其是否符合您的实验需求;若有疑问,也可联系我们的技术团队获取协助。

产品详情

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

How are conjugated primary antibodies validated?
This conjugated primary antibody is released using a quantitative quality control method that evaluates binding affinity post-conjugation and efficiency of antibody labeling.
For suitable applications and species reactivity, please refer to the unconjugated version of this clone.

性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Protein A
存储溶液
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: 68% PBS, 30% Glycerol (glycerin, glycerine), 1% BSA
运输条件
Blue Ice
推荐的短期储存时间
1-2 weeks
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle|Store in the dark

补充信息

This supplementary information is collated from multiple sources and compiled automatically.

Extracellular matrix protein 1 often called ECM1 is a matrix protein involved in various mechanical functions in the body. This protein weighs approximately 61 kDa and is widely expressed in human tissues including skin bone lung and brain. ECM1 also goes by the name H3300 vector used in some experimental contexts. Being an extracellular matrix (ECM) component ECM1 plays roles in tissue organization influencing matrix proteins' structural integrity.
Biological function summary

ECM1 contributes to cell-matrix interactions and regulates various cell behaviors such as adhesion proliferation and differentiation. It does this by binding to other ECM proteins and is known not to be part of a specific complex. ECM1 facilitates communication between the cellular environment and matrix thereby supporting the architecture and dynamics of tissues. It modulates angiogenesis linking it with processes like wound healing and vascular development.

Pathways

ECM1 functions within the context of key signaling routes such as the PI3K/AKT pathway known for roles in cell growth and survival. ECM1 interacts with other proteins including matrix metalloproteinases contributing to matrix remodeling activities important for cellular migration and invasion. Cumulatively these interactions highlight ECM1’s place in connective tissue organization and regenerative processes.

ECM1’s dysregulation links it with lipoid proteinosis and skin conditions like Atopic Dermatitis. Imbalances in ECM1 expression or function can lead to abnormal ECM assembly influencing these diseases' development. Moreover abnormalities in ECM1 can alter the behavior of related proteins such as collagen impacting skin integrity and permeability. Understanding ECM1’s role could provide insights into therapeutic strategies for these conditions.

产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

靶点信息

Involved in endochondral bone formation as negative regulator of bone mineralization. Stimulates the proliferation of endothelial cells and promotes angiogenesis. Inhibits MMP9 proteolytic activity.
See full target information Extracellular matrix protein 1

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详情请参阅我们的条款与条件。

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Alternative Version
Primary Antibodies

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Anti-Extracellular matrix protein 1 antibody [EPR6701] - BSA and Azide free

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