JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB312759

重组Alexa Fluor® 568荧光Anti-Cytokeratin 15抗体[EPR1614Y]

Alexa Fluor® 568 Anti-Cytokeratin 15 antibody [EPR1614Y]

Be the first to review this product! Submit a review

|

(0 Publication)

Rabbit Recombinant Monoclonal K1C15 antibody - conjugated to Alexa Fluor® 568.

查看别名

KRTB, KRT15, Cytokeratin-15, Keratin-15, CK-15, K15

不同偶联物与剂型 (10)

  • Unconjugated

    Anti-Cytokeratin 15 antibody [EPR1614Y]

  • 660 APC

    APC Anti-Cytokeratin 15 antibody [EPR1614Y]

  • HRP

    HRP Anti-Cytokeratin 15 antibody [EPR1614Y]

  • 617 Alexa Fluor® 594

    Alexa Fluor® 594 Anti-Cykeratin 15 antibody [EPR1614Y]

  • 578 PE

    PE Anti-Cytokeratin 15 antibody [EPR1614Y]

  • 775 Alexa Fluor® 750

    Alexa Fluor® 750 Anti-Cytokeratin 15 antibody [EPR1614Y]

  • 665 Alexa Fluor® 647

    Alexa Fluor® 647 Anti-Cytokeratin 15 antibody [EPR1614Y]

  • Carrier free

    Anti-Cytokeratin 15 antibody [EPR1614Y] - BSA and Azide free

  • 519 Alexa Fluor® 488

    Alexa Fluor® 488 Anti-Cytokeratin 15 antibody [EPR1614Y]

  • 565 Alexa Fluor® 555

    Alexa Fluor® 555 Anti-Cytokeratin 15 antibody [EPR1614Y]

关键信息

宿主种属

Rabbit

克隆

Monoclonal

克隆号

EPR1614Y

亚型

IgG

偶联物

Alexa Fluor® 568

激发波长/发射波长

Ex: 578nm, Em: 603nm

不含载体蛋白

No

应用

Antibody Labelling, Target Binding Affinity

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

产品详情

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

How are conjugated primary antibodies validated?
This conjugated primary antibody is released using a quantitative quality control method that evaluates binding affinity post-conjugation and efficiency of antibody labeling.
For suitable applications and species reactivity, please refer to the unconjugated version of this clone.

性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Protein A
存储溶液
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: 68% PBS, 30% Glycerol (glycerin, glycerine), 1% BSA
运输条件
Blue Ice
推荐的短期储存时间
1-2 weeks
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle|Store in the dark

补充信息

This supplementary information is collated from multiple sources and compiled automatically.

Cytokeratin 15 often abbreviated as CK15 bsa-15 or keratin 15 is an intermediate filament protein known for its role in the structural integrity of epithelial cells. It weighs approximately 50 kilodaltons. This protein is mainly expressed in the basal layer of stratified squamous epithelia such as the epidermis and the hair follicle. CK15 is an essential part of the cytoskeleton contributing to cell shape and mechanical resilience.
Biological function summary

CK15 plays a significant role in maintaining epithelial stem cell populations. It is part of the keratin protein family where it forms a complex network with other cytokeratins to support epithelial cell stability. CK15 has been shown to mark epithelial progenitor cells hinting at its role in tissue regeneration and repair. Its expression levels often reflect the cellular origin and differentiation state particularly in the skin and associated structures.

Pathways

CK15 is involved in pathways related to epithelial cell differentiation and homeostasis. It interacts within the cytoskeletal network alongside other cytokeratins like keratin 5. CK15 contributes to pathways that regulate cell proliferation and differentiation. It participates in the wound healing process where keratin 6 and keratin 17 also play important roles. This involvement allows it to impact how epithelial cells respond to and repair after damage.

CK15 has been associated with skin disorders and certain types of cancers. Its expression is often altered in squamous cell carcinoma and basal cell carcinoma where abnormal CK15 levels can influence tumor behavior. Additionally changes in CK15 expression are linked to alopecia relating it to proteins like keratin 5 and keratin 8 which have similar expression patterns in hair follicles. Understanding CK15's role may aid in developing biomarkers for diagnosis and therapeutic targets.

产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Abcam Product Promise

我们致力于为您的研究提供高质量的试剂,为您科研的每一步提供支持。若我们的产品未能达到预期性能,我们向您提供 Abcam Product Promise 保障。
详情请参阅我们的条款与条件。

关联产品

Select an associated product type
Alternative Version
Primary Antibodies

AB239850

Anti-Cytokeratin 15 antibody [EPR1614Y] - BSA and Azide free

primary-antibodies

cytokeratin-15-antibody-epr1614y-bsa-and-azide-free-ab239850

0

(0 reviews)

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com