AB311933

重组Alexa Fluor® 555荧光Anti-RPA32/RPA2抗体[EPR2877Y]

Alexa Fluor® 555 Anti-RPA32/RPA2 antibody [EPR2877Y]

RabMAb
Recombinant
了解详情

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Rabbit Recombinant Monoclonal RPA32/RPA2 antibody - conjugated to Alexa Fluor® 555.

查看别名

REPA2, RPA32, RPA34, RPA2, Replication protein A 32 kDa subunit, RP-A p32, Replication factor A protein 2, Replication protein A 34 kDa subunit, RF-A protein 2, RP-A p34

不同偶联物与剂型 (11)

665 Alexa Fluor® 647

Alexa Fluor® 647 Anti-RPA32/RPA2 antibody [EPR2877Y]
519 Alexa Fluor® 488

Alexa Fluor® 488 Anti-RPA32/RPA2 antibody [EPR2877Y]
578 PE

PE Anti-RPA32/RPA2 antibody [EPR2877Y]
660 APC

APC Anti-RPA32/RPA2 antibody [EPR2877Y]
HRP

HRP Anti-RPA32/RPA2 antibody [EPR2877Y]
617 Alexa Fluor® 594

Alexa Fluor® 594 Anti-RPA32/RPA2 antibody [EPR2877Y]
603 Alexa Fluor® 568

Alexa Fluor® 568 Anti-RPA32/RPA2 antibody [EPR2877Y]
775 Alexa Fluor® 750

Alexa Fluor® 750 Anti-RPA32/RPA2 antibody [EPR2877Y]
Unconjugated

Anti-RPA32/RPA2 antibody [EPR2877Y]
Carrier free

Anti-RPA32/RPA2 antibody [EPR2877Y] - BSA and Azide free
Unconjugated

Anti-RPA32/RPA2 antibody [EPR2877Y] - Mouse IgG1 (Chimeric)

关键信息

宿主种属

Rabbit

克隆

Monoclonal

克隆号

EPR2877Y

亚型

IgG

偶联物

Alexa Fluor® 555

激发波长/发射波长

Ex: 555nm, Em: 565nm

不含载体蛋白

应用

Target Binding Affinity, Antibody Labelling

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

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产品详情

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

How are conjugated primary antibodies validated?
This conjugated primary antibody is released using a quantitative quality control method that evaluates binding affinity post-conjugation and efficiency of antibody labeling.
For suitable applications and species reactivity, please refer to the unconjugated version of this clone.

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性能和储存信息

形式

Liquid

纯化工艺

Affinity purification Protein A

存储溶液

pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 30% Glycerol (glycerin, glycerine), 1% BSA

运输条件

Blue Ice

分装信息

Upon delivery aliquot

储存信息

Avoid freeze / thaw cycle|Store in the dark

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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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靶点信息

As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. In the cellular response to DNA damage, the RPA complex controls DNA repair and DNA damage checkpoint activation. Through recruitment of ATRIP activates the ATR kinase a master regulator of the DNA damage response. It is required for the recruitment of the DNA double-strand break repair factors RAD51 and RAD52 to chromatin in response to DNA damage. Also recruits to sites of DNA damage proteins like XPA and XPG that are involved in nucleotide excision repair and is required for this mechanism of DNA repair. Also plays a role in base excision repair (BER) probably through interaction with UNG. Also recruits SMARCAL1/HARP, which is involved in replication fork restart, to sites of DNA damage. May also play a role in telomere maintenance. RPA stimulates 5'-3' helicase activity of BRIP1/FANCJ (PubMed : 17596542).

See full target information RPA2

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Abcam Product Promise

我们致力于为您的研究提供高质量的试剂，为您科研的每一步提供支持。若我们的产品未能达到预期性能，我们向您提供 Abcam Product Promise 保障。

详情请参阅我们的条款与条件。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

重组Alexa Fluor® 555荧光Anti-RPA32/RPA2抗体[EPR2877Y]