重组Alexa Fluor® 488荧光Anti-CD7抗体[EPR4242]
Alexa Fluor® 488 Anti-CD7 antibody [EPR4242]
- RabMAb
- Recombinant
- 了解详情
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(1 Publication)
Rabbit Recombinant Monoclonal CD7 antibody - conjugated to Alexa Fluor® 488. Suitable for ICC/IF and reacts with Human samples. Cited in 1 publication.
查看别名
CD7, T-cell antigen CD7, GP40, T-cell leukemia antigen, T-cell surface antigen Leu-9, TP41
- ICC/IF
Lab
Immunocytochemistry/ Immunofluorescence - Alexa Fluor® 488 Anti-CD7 antibody [EPR4242] (AB199022)
ab199022 staining CD7 in Jurkat cells. The cells were fixed with 100% methanol (5min), permeabilized with 0.1% Triton X-100 for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween for 1h. The cells were then incubated overnight at +4°C with ab199769 at 1/50 dilution (shown in green). Nuclear DNA was labelled with DAPI (shown in blue).
Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8). This product also gave positive signal under the same testing conditions in Jurkat cells fixed with 4% formaldehyde (10min).
不同偶联物与剂型 (8)
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565 Alexa Fluor® 555
Alexa Fluor® 555 Anti-CD7 antibody [EPR4242]
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617 Alexa Fluor® 594
Alexa Fluor® 594 Anti-CD7 antibody [EPR4242]
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665 Alexa Fluor® 647
Alexa Fluor® 647 Anti-CD7 antibody [EPR4242]
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578 PE
PE Anti-CD7 antibody [EPR4242]
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660 APC
APC Anti-CD7 antibody [EPR4242]
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HRP Anti-CD7 antibody [EPR4242]
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603 Alexa Fluor® 568
Alexa Fluor® 568 Anti-CD7 antibody [EPR4242]
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775 Alexa Fluor® 750
Alexa Fluor® 750 Anti-CD7 antibody [EPR4242]
反应性数据
产品详情
Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free batch production
For more information, read more on recombinant antibodies.
Alexa Fluor® is a registered trademark of Molecular Probes, Inc, a Thermo Fisher Scientific Company. The Alexa Fluor® dye included in this product is provided under an intellectual property license from Life Technologies Corporation. As this product contains the Alexa Fluor® dye, the purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). As this product contains the Alexa Fluor® dye the sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: in manufacturing; (ii) to provide a service, information, or data in return for payment (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are sold for use in research. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.
性能和储存信息
形式
纯化工艺
存储溶液
运输条件
推荐的短期储存时间
推荐的短期储存条件
推荐的长期储存条件
分装信息
储存信息
补充信息
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
CD7 plays a role in modulating interactions between immune cells without being part of a larger complex. It bridges interactions promoting immune responses by influencing T cell proliferation and cytokine production. CD7 control is important in regulating immune response intensity and provides an essential checkpoint in immune system modulation. Variations in CD7 function can significantly influence immune cell behavior impacting host defense mechanisms.
Pathways
CD7 participates in immune signaling pathways such as the T-cell receptor (TCR) signaling pathway. This pathway is essential for T cell activation and involves proteins like CD3 and ZAP-70 which work together with CD7 to transduce activation signals. Alterations in the CD7 pathway can affect the downstream signaling events leading to changes in immune cell activation and function.
产品实验方案
- Visit the General protocols
- Visit the Troubleshooting
靶点信息
文献 (1)
Recent publications for all applications. Explore the full list and refine your search
Frontiers in endocrinology 9:616 PubMed30386299
2018
Applications
Unspecified application
Species
Unspecified reactive species
Abcam Product Promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com