Anti-ALDH3A1抗体(ab76976)
Key features and details
- Rabbit polyclonal to ALDH3A1
- Suitable for: WB, ICC/IF, IHC-P
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
概述
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产品名称
Anti-ALDH3A1抗体
参阅全部 ALDH3A1 一抗 -
描述
兔多克隆抗体to ALDH3A1 -
宿主
Rabbit -
特异性
This antibody is predicted to have no cross reactivity to ALDH3A2. -
经测试应用
适用于: WB, ICC/IF, IHC-Pmore details -
种属反应性
与反应: Mouse, Rat, Human -
免疫原
Synthetic peptide (Human): a 13 amino acid peptide from near the C terminus of human ALDH3A1. (NP_000682).
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab76976于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 50 kDa.
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| ICC/IF |
Use at an assay dependent concentration.
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| IHC-P |
Use at an assay dependent concentration.
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| 说明 |
|---|
|
WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 50 kDa. |
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ICC/IF
Use at an assay dependent concentration. |
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IHC-P
Use at an assay dependent concentration. |
靶标
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功能
ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes. -
组织特异性
High levels in stomach, esophagus and lung; low level in the liver and kidney. -
序列相似性
Belongs to the aldehyde dehydrogenase family. -
细胞定位
Cytoplasm. - Information by UniProt
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数据库链接
- Entrez Gene: 218 Human
- Entrez Gene: 11670 Mouse
- Entrez Gene: 25375 Rat
- Omim: 100660 Human
- SwissProt: P30838 Human
- SwissProt: P47739 Mouse
- SwissProt: P11883 Rat
- Unigene: 531682 Human
see all -
别名
- Acetaldehyde dehydrogenase 3 antibody
- AHD 4 antibody
- AHD C antibody
see all
图片
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Western blot - Anti-ALDH3A1 antibody (ab76976)Lane 1 : Anti-ALDH3A1 antibody (ab76976) at 1 µg/ml
Lane 2 : Anti-ALDH3A1 antibody (ab76976) at 2 µg/ml
All lanes : human stomach lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 50 kDa
Observed band size: 50 kDa
数据表及文件
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SDS download
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Datasheet download
文献 (28)
ab76976 被引用在 28 文献中.
- Nishtala K et al. Quantitative Proteomics Reveals Molecular Network Driving Stromal Cell Differentiation: Implications for Corneal Wound Healing. Int J Mol Sci 23:N/A (2022). PubMed: 35269714
- Matsumoto R et al. Nuclear Factor Erythroid 2-Related Factor 2 Depletion Sensitizes Pancreatic Cancer Cells to Gemcitabine via Aldehyde Dehydrogenase 3a1 Repression. J Pharmacol Exp Ther 379:33-40 (2021). PubMed: 34321315
- Zheng C et al. Identification and validation of a metabolism-related model and associated with tumor-infiltrating lymphocytes in p53 mutant lung adenocarcinoma patients. Ann Transl Med 9:1312 (2021). PubMed: 34532449
- Khorolskaya JI et al. Derivation and Characterization of EGFP-Labeled Rabbit Limbal Mesenchymal Stem Cells and Their Potential for Research in Regenerative Ophthalmology. Biomedicines 9:N/A (2021). PubMed: 34572321
- Fernández-Pérez J et al. The effect of prior long-term recellularization with keratocytes of decellularized porcine corneas implanted in a rabbit anterior lamellar keratoplasty model. PLoS One 16:e0245406 (2021). PubMed: 34061862