Anti-ALDH1A1抗体(ab9883)
Key features and details
- Goat polyclonal to ALDH1A1
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术,可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-ALDH1A1抗体
参阅全部 ALDH1A1 一抗 -
描述
山羊多克隆抗体to ALDH1A1 -
宿主
Goat -
特异性
This antibody may cross-react with ALDH1A2 (GeneID 8854) with one residue difference from this design, and with ALDH2 (GeneID 217) with two residues difference from this design. Please note that ALDH1A2 is known to be alternatively spliced under some conditions (37kDa).
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经测试应用
适用于: WBmore details
不适用于: ICC -
种属反应性
与反应: Mouse, Rat, Human
预测可用于: Cow -
免疫原
Synthetic peptide: EVKTVTVKISQKNS, corresponding to C terminal amino acids 488-501 of Human Aldehyde Dehydrogenase 1.
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常规说明
A protease inhibitor that inhibits fibrin clot formation.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 99% Tris buffered saline, 0.5% BSA -
Concentration information loading...
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纯度
Immunogen affinity purified -
纯化说明
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
Primary antibody说明
A protease inhibitor that inhibits fibrin clot formation. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
应用
应用 | Ab评论 | 说明 |
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WB | (2) |
Use a concentration of 0.3 - 1 µg/ml. Predicted molecular weight: 55 kDa.
1 hour primary incubation is recommended for this product. |
说明 |
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WB
Use a concentration of 0.3 - 1 µg/ml. Predicted molecular weight: 55 kDa. 1 hour primary incubation is recommended for this product. |
靶标
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功能
Binds free retinal and cellular retinol-binding protein-bound retinal. Can convert/oxidize retinaldehyde to retinoic acid. -
通路
Cofactor metabolism; retinol metabolism. -
序列相似性
Belongs to the aldehyde dehydrogenase family. -
细胞定位
Cytoplasm. - Information by UniProt
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数据库链接
- Entrez Gene: 281615 Cow
- Entrez Gene: 216 Human
- Entrez Gene: 11668 Mouse
- Entrez Gene: 24188 Rat
- Omim: 100640 Human
- SwissProt: P48644 Cow
- SwissProt: P00352 Human
- SwissProt: P24549 Mouse
see all -
别名
- Acetaldehyde dehydrogenase 1 antibody
- AHD2 antibody
- AL1A1_HUMAN antibody
see all
图片
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All lanes : Anti-ALDH1A1 antibody (ab9883) at 0.3 µg/ml
Lane 1 : Human liver lysate (protein in RIPA buffer)
Lane 2 : Rat liver lysate (protein in RIPA buffer)
Lane 3 : Mouse liver lysate (protein in RIPA buffer)
Lysates/proteins at 35 µg per lane.
Predicted band size: 55 kDaDetected by chemiluminescence.
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Anti-ALDH1A1 antibody (ab9883) at 1/500 dilution + MDBK cell lysate at 100 µg
Secondary
HRP-conjugated Donkey anti-goat IgG
Predicted band size: 55 kDa
数据表及文件
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Datasheet download
文献 (20)
ab9883 被引用在 20 文献中.
- Surmelioglu O et al. Predictive value of ALDH1 and CD44 positivity for radiotherapy response and prognosis in early-stage glottic laryngeal squamous cell carcinoma. Pol J Pathol 73:43-49 (2022). PubMed: 35848480
- Fernández-Pérez J et al. The effect of prior long-term recellularization with keratocytes of decellularized porcine corneas implanted in a rabbit anterior lamellar keratoplasty model. PLoS One 16:e0245406 (2021). PubMed: 34061862
- Sharaf K et al. Discrimination of Cancer Stem Cell Markers ALDH1A1, BCL11B, BMI-1, and CD44 in Different Tissues of HNSCC Patients. Curr Oncol 28:2763-2774 (2021). PubMed: 34287293
- Flori L et al. Development of Fortified Citrus Olive Oils: From Their Production to Their Nutraceutical Properties on the Cardiovascular System. Nutrients 12:N/A (2020). PubMed: 32471156
- Macaluso M et al. By-Products from Winemaking and Olive Mill Value Chains for the Enrichment of Refined Olive Oil: Technological Challenges and Nutraceutical Features. Foods 9:N/A (2020). PubMed: 33019655