Anti-Albumin抗体(ab106582)
Key features and details
- Chicken polyclonal to Albumin
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Rat, Human
- Isotype: IgY
概述
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产品名称
Anti-Albumin抗体
参阅全部 Albumin 一抗 -
描述
鸡多克隆抗体to Albumin -
宿主
Chicken -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Mouse, Rat, Human -
免疫原
Synthetic peptide corresponding to Human Albumin (internal sequence). The immunogen is located within amino acids 340 - 390 of Albumin.
Database link: P02768 -
阳性对照
- Mouse liver lysate; Human liver tissue
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常规说明
Antibodies should not be exposed to prolonged high temperatures.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at +4°C. -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgY -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab106582于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 69 kDa.
|
|
| IHC-P | (7) |
Use a concentration of 2.5 - 20 µg/ml.
|
| IF |
Use a concentration of 20 µg/ml.
|
| 说明 |
|---|
|
WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 69 kDa. |
|
IHC-P
Use a concentration of 2.5 - 20 µg/ml. |
|
IF
Use a concentration of 20 µg/ml. |
靶标
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功能
Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. -
组织特异性
Plasma. -
疾病相关
Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population. -
序列相似性
Belongs to the ALB/AFP/VDB family.
Contains 3 albumin domains. -
翻译后修饰
Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.
Glycated in diabetic patients.
Phosphorylation sites are present in the extracelllular medium.
Acetylated on Lys-223 by acetylsalicylic acid. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 213 Human
- Entrez Gene: 11657 Mouse
- Entrez Gene: 24186 Rat
- Omim: 103600 Human
- SwissProt: P02768 Human
- SwissProt: P07724 Mouse
- SwissProt: P02770 Rat
- Unigene: 418167 Human
see all -
形式
There are 2 isoforms produced by alternative splicing. -
别名
- alb antibody
- ALBU_HUMAN antibody
- Albumin (32 AA) antibody
see all
图片
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Immunofluorescence - Anti-Albumin antibody (ab106582)
Immunofluorescence analysis of paraffin embedded mouse liver tissue section labelling Albumin with ab106582 at 20 µg/mL.
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (52)
ab106582 被引用在 52 文献中.
- Wu MC et al. TAT peptide at treatment-level concentrations crossed brain endothelial cell monolayer independent of receptor-mediated endocytosis or peptide-inflicted barrier disruption. PLoS One 18:e0292681 (2023). PubMed: 37819924
- Luo W et al. MD2 deficiency prevents high-fat diet-induced AMPK suppression and lipid accumulation through regulating TBK1 in non-alcoholic fatty liver disease. Clin Transl Med 12:e777 (2022). PubMed: 35343085
- Dobric A et al. Cigarette Smoke Exposure Induces Neurocognitive Impairments and Neuropathological Changes in the Hippocampus. Front Mol Neurosci 15:893083 (2022). PubMed: 35656006
- Wang N et al. Identification of novel prognostic risk signature of breast cancer based on ferroptosis-related genes. Sci Rep 12:13766 (2022). PubMed: 35962042
- Miri-Lavasani Z et al. Conjugated Linoleic Acid Treatment Attenuates Cancerous features in Hepatocellular Carcinoma Cells. Stem Cells Int 2022:1850305 (2022). PubMed: 36132168